Predictors, prognosis and costs of prolonged intensive care unit stay after surgery for type A aortic dissection

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F24%3A43927334" target="_blank" >RIV/00064173:_____/24:43927334 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/24:43927334

Výsledek na webu

<a href="https://doi.org/10.23736/S0375-9393.24.18210-7" target="_blank" >https://doi.org/10.23736/S0375-9393.24.18210-7</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.23736/S0375-9393.24.18210-7" target="_blank" >10.23736/S0375-9393.24.18210-7</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Predictors, prognosis and costs of prolonged intensive care unit stay after surgery for type A aortic dissection

Popis výsledku v původním jazyce

BACKGROUND: The outcomes after prolonged treatment in the intensive care unit (ICU) after surgery for Stanford type A aortic dissection (TAAD) have not been previously investigated. METHODS: This analysis included 3538 patients from a multicenter study who underwent surgery for acute TAAD and were admitted to the cardiac surgical ICU. RESULTS: The mean length of stay in the cardiac surgical ICU was 9.9+-9.5 days. The mean overall costs of treatment in the cardiac surgical ICU 24086+-32084 EUR. In-hospital mortality was 14.8% and 5-year mortality was 30.5%. Adjusted analyses showed that prolonged ICU stay was associated with significantly lower risk of in-hospital mortality (adjusted OR 0.971, 95%CI 0.959-0.982), and of five-year mortality (adjusted OR 0.970, 95%CI 0.962-0.977), respectively. Propensity score matching analysis yielded 870 pairs of patients with short ICU stay (2-5 days) and long ICU stay (&gt;5 days) with balanced baseline, operative and postoperative variables. Patients with prolonged ICU stay (&gt;5 days) had significantly lower in-hospital mortality (8.9% vs. 17.4%, &lt;0.001) and 5-year mortality (28.2% vs. 30.7%, P=0.007) compared to patients with short ICU-stay (2-5 days). CONCLUSIONS: Prolonged ICU stay was common after surgery for acute TAAD. However, when adjusted for multiple baseline and operative variables as well as adverse postoperative events and the cluster effect of hospitals, it was associated with favorable survival up to 5 years after surgery.

Název v anglickém jazyce

Predictors, prognosis and costs of prolonged intensive care unit stay after surgery for type A aortic dissection

Popis výsledku anglicky

BACKGROUND: The outcomes after prolonged treatment in the intensive care unit (ICU) after surgery for Stanford type A aortic dissection (TAAD) have not been previously investigated. METHODS: This analysis included 3538 patients from a multicenter study who underwent surgery for acute TAAD and were admitted to the cardiac surgical ICU. RESULTS: The mean length of stay in the cardiac surgical ICU was 9.9+-9.5 days. The mean overall costs of treatment in the cardiac surgical ICU 24086+-32084 EUR. In-hospital mortality was 14.8% and 5-year mortality was 30.5%. Adjusted analyses showed that prolonged ICU stay was associated with significantly lower risk of in-hospital mortality (adjusted OR 0.971, 95%CI 0.959-0.982), and of five-year mortality (adjusted OR 0.970, 95%CI 0.962-0.977), respectively. Propensity score matching analysis yielded 870 pairs of patients with short ICU stay (2-5 days) and long ICU stay (&gt;5 days) with balanced baseline, operative and postoperative variables. Patients with prolonged ICU stay (&gt;5 days) had significantly lower in-hospital mortality (8.9% vs. 17.4%, &lt;0.001) and 5-year mortality (28.2% vs. 30.7%, P=0.007) compared to patients with short ICU-stay (2-5 days). CONCLUSIONS: Prolonged ICU stay was common after surgery for acute TAAD. However, when adjusted for multiple baseline and operative variables as well as adverse postoperative events and the cluster effect of hospitals, it was associated with favorable survival up to 5 years after surgery.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Minerva Anestesiologica

ISSN

0375-9393

e-ISSN

1827-1596

Svazek periodika

90

Číslo periodika v rámci svazku

7-8

Stát vydavatele periodika

IT - Italská republika

Počet stran výsledku

8

Strana od-do

654-661

Kód UT WoS článku

001319898700012

EID výsledku v databázi Scopus

2-s2.0-85199127468