Short-term low-carbohydrate diet decreases body weight and fat mass but not muscle strength in children and young people with type 1 diabetes

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F25%3A10500705" target="_blank" >RIV/00064203:_____/25:10500705 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60460709:41210/25:103111 RIV/00216208:11130/25:10500705 RIV/00216208:11320/25:10500705

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=~zy3KKUt4Y" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=~zy3KKUt4Y</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/s41430-025-01658-2" target="_blank" >10.1038/s41430-025-01658-2</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Short-term low-carbohydrate diet decreases body weight and fat mass but not muscle strength in children and young people with type 1 diabetes

Popis výsledku v původním jazyce

AIMS: We investigated whether a short period of tightly controlled low-carbohydrate diet (LCD) leads to a change in body weight, body composition, and muscle strength in children and young people with diabetes (CYPwD). METHODS: Thirty-five CYPwD were recruited into this randomized controlled cross-over study (20 female; age 14.5 +- 2.9 years). The interventions were five and five weeks of ready-made food box deliveries of isocaloric diets in random order: either LCD (94.5 +- 4.7 g/day) or recommended carbohydrate diet (RCD) (191 +- 19.2 g/day). The outcomes were body weight and body mass index (BMI) standard deviation scores (SDS), body fat percentage assessed by bioimpedance and muscle strength assessed by jumping mechanography at the end of each dietary intervention. The Welch two-sample t-tests were used to determine the difference in outcomes. RESULTS: At the end of the LCD period, the participants had significantly lower body weight and BMI SDS than at the end of the RCD period (61.7 kg vs. 62.6 kg, P &lt; 0.001, and 22.3 kg/m(2) vs. 22.7 kg/m(2), P &lt; 0.001) and (0.84 SD vs. 0.94 SD, P &lt; 0.001, and 0.81 SD vs. 0.91 SD, P &lt; 0.001). The body fat percentage was lower at the end of the LCD period (24.5% vs. 25.3%, P = 0.001). Dynamic muscle functions did not differ significantly at the end of the intervention periods. CONCLUSIONS: We demonstrated that a short-term low-carbohydrate diet is able to decrease body weight, BMI, and decrease the percentage of body fat in CYPwD without negatively affecting their muscle function.

Název v anglickém jazyce

Short-term low-carbohydrate diet decreases body weight and fat mass but not muscle strength in children and young people with type 1 diabetes

Popis výsledku anglicky

AIMS: We investigated whether a short period of tightly controlled low-carbohydrate diet (LCD) leads to a change in body weight, body composition, and muscle strength in children and young people with diabetes (CYPwD). METHODS: Thirty-five CYPwD were recruited into this randomized controlled cross-over study (20 female; age 14.5 +- 2.9 years). The interventions were five and five weeks of ready-made food box deliveries of isocaloric diets in random order: either LCD (94.5 +- 4.7 g/day) or recommended carbohydrate diet (RCD) (191 +- 19.2 g/day). The outcomes were body weight and body mass index (BMI) standard deviation scores (SDS), body fat percentage assessed by bioimpedance and muscle strength assessed by jumping mechanography at the end of each dietary intervention. The Welch two-sample t-tests were used to determine the difference in outcomes. RESULTS: At the end of the LCD period, the participants had significantly lower body weight and BMI SDS than at the end of the RCD period (61.7 kg vs. 62.6 kg, P &lt; 0.001, and 22.3 kg/m(2) vs. 22.7 kg/m(2), P &lt; 0.001) and (0.84 SD vs. 0.94 SD, P &lt; 0.001, and 0.81 SD vs. 0.91 SD, P &lt; 0.001). The body fat percentage was lower at the end of the LCD period (24.5% vs. 25.3%, P = 0.001). Dynamic muscle functions did not differ significantly at the end of the intervention periods. CONCLUSIONS: We demonstrated that a short-term low-carbohydrate diet is able to decrease body weight, BMI, and decrease the percentage of body fat in CYPwD without negatively affecting their muscle function.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30209 - Paediatrics

Projekt

<a href="/cs/project/NU21-01-00085" target="_blank" >NU21-01-00085: Vliv nízkosacharidové diety na kontrolu diabetu 1. typu a rozvoj ostrůvkové autoimunity</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European Journal of Clinical Nutrition

ISSN

0954-3007

e-ISSN

1476-5640

Svazek periodika

79

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

5

Strana od-do

1149-1153

Kód UT WoS článku

001556446800001

EID výsledku v databázi Scopus

2-s2.0-105013788043