How much is too much?Threshold dosedistributions for 5 food allergens

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064211%3A_____%2F14%3A%230000377" target="_blank" >RIV/00064211:_____/14:#0000377 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11140/15:10326604

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.jaci.2014.10.047" target="_blank" >http://dx.doi.org/10.1016/j.jaci.2014.10.047</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jaci.2014.10.047" target="_blank" >10.1016/j.jaci.2014.10.047</a>

Jazyk výsledku

angličtina

Název v původním jazyce

How much is too much?Threshold dosedistributions for 5 food allergens

Popis výsledku v původním jazyce

Background: Precautionary labeling is used to warn consumers of the presence of unintended allergens, but the lack of agreed allergen thresholds can result in confusion and risk taking by patients with food allergy. The lack of data on threshold doses below which subjects are unlikely to react is preventing the development of evidence-based allergen management strategies that are understood by clinician and patient alike.Objective: We sought to define threshold dose distributions for 5 major allergenicfoods in the European population. Methods: Patients with food allergy were drawn from the EuroPrevall birth cohort, community surveys, and outpatient clinic studies and invited to undergo a food challenge. Low-dose,double-blind, placebo-controlled food challenges were undertaken with commercially available food ingredients (peanut, hazelnut, celery, fish, and shrimp) blinded into common matrices. Dose distributions were modeled by using interval-censoring survival analysis with 3 paramet

Název v anglickém jazyce

How much is too much?Threshold dosedistributions for 5 food allergens

Popis výsledku anglicky

Background: Precautionary labeling is used to warn consumers of the presence of unintended allergens, but the lack of agreed allergen thresholds can result in confusion and risk taking by patients with food allergy. The lack of data on threshold doses below which subjects are unlikely to react is preventing the development of evidence-based allergen management strategies that are understood by clinician and patient alike.Objective: We sought to define threshold dose distributions for 5 major allergenicfoods in the European population. Methods: Patients with food allergy were drawn from the EuroPrevall birth cohort, community surveys, and outpatient clinic studies and invited to undergo a food challenge. Low-dose,double-blind, placebo-controlled food challenges were undertaken with commercially available food ingredients (peanut, hazelnut, celery, fish, and shrimp) blinded into common matrices. Dose distributions were modeled by using interval-censoring survival analysis with 3 paramet

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FG - Pediatrie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Allergy and Clinical Immunology

ISSN

0091-6749

e-ISSN

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Svazek periodika

2015

Číslo periodika v rámci svazku

135

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

964-971

Kód UT WoS článku

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EID výsledku v databázi Scopus

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