Regional differences of vasodilatation and vasomotion response to local heating in human cutaneous microcirculation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F15%3A00068438" target="_blank" >RIV/00159816:_____/15:00068438 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1024/0301-1526/a000469" target="_blank" >http://dx.doi.org/10.1024/0301-1526/a000469</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1024/0301-1526/a000469" target="_blank" >10.1024/0301-1526/a000469</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Regional differences of vasodilatation and vasomotion response to local heating in human cutaneous microcirculation

Popis výsledku v původním jazyce

Background: The aim of this study was to evaluate the vasodilatation and vasomotion response to local heating in the cutaneous microcirculation of the ankle, dorsum of foot and forearm. Recently, it has been suggested that this response differs between the forearm and the leg. Probands and methods: Twenty-nine young healthy adults were recruited. They underwent measurement by laser Doppler flowmetry (LDF) in three sites of the body (ankle, dorsum of foot, forearm). Percentage change of the median flow of the skin before and after provocation and normalised perfusion flow to maximal dilation (cutaneous vascular conductance - CVC % Max) during short provocation test were monitored. Spectral analysis of laser Doppler flowmetry signals was performed using the fast Fourier transform algorithm. Results: Significant differences were found in CVC % Max between ankle/dorsum (45.18 +/- 6.38% Max vs. 51.24 +/- 6.87% Max, respectively; p &lt; 0.05) and between ankle/forearm (45.18 +/- 6.38% Max vs. 54.49 +/- 5.37% Max, respectively; p &lt; 0.05). Percentage change of flux after provocation has revealed significant differences between ankle/dorsum (394.1 +/- 204.5% vs. 577.4 +/- 273.5%, respectively; p &lt; 0.05) and ankle/forearm (394.1 +/- 204.5% vs. 637.1 +/- 324.7%, respectively; p &lt; 0.05). Total spectral activity of vasomotion has differed between ankle/dorsum and ankle/forearm: 69.59 [49.58-96.04] vs. 93.01 [73.15-121.8] (p &lt; 0.05) and 69.59 [49.58-96.04] vs. 107.5 [80.55-155.8] (p &lt; 0.05), respectively. Conclusions: Cutaneous microcirculation exhibits regional differences. Significant variability of function between ankle and dorsum of foot suggests that leg microcirculation is not uniform.

Název v anglickém jazyce

Regional differences of vasodilatation and vasomotion response to local heating in human cutaneous microcirculation

Popis výsledku anglicky

Background: The aim of this study was to evaluate the vasodilatation and vasomotion response to local heating in the cutaneous microcirculation of the ankle, dorsum of foot and forearm. Recently, it has been suggested that this response differs between the forearm and the leg. Probands and methods: Twenty-nine young healthy adults were recruited. They underwent measurement by laser Doppler flowmetry (LDF) in three sites of the body (ankle, dorsum of foot, forearm). Percentage change of the median flow of the skin before and after provocation and normalised perfusion flow to maximal dilation (cutaneous vascular conductance - CVC % Max) during short provocation test were monitored. Spectral analysis of laser Doppler flowmetry signals was performed using the fast Fourier transform algorithm. Results: Significant differences were found in CVC % Max between ankle/dorsum (45.18 +/- 6.38% Max vs. 51.24 +/- 6.87% Max, respectively; p &lt; 0.05) and between ankle/forearm (45.18 +/- 6.38% Max vs. 54.49 +/- 5.37% Max, respectively; p &lt; 0.05). Percentage change of flux after provocation has revealed significant differences between ankle/dorsum (394.1 +/- 204.5% vs. 577.4 +/- 273.5%, respectively; p &lt; 0.05) and ankle/forearm (394.1 +/- 204.5% vs. 637.1 +/- 324.7%, respectively; p &lt; 0.05). Total spectral activity of vasomotion has differed between ankle/dorsum and ankle/forearm: 69.59 [49.58-96.04] vs. 93.01 [73.15-121.8] (p &lt; 0.05) and 69.59 [49.58-96.04] vs. 107.5 [80.55-155.8] (p &lt; 0.05), respectively. Conclusions: Cutaneous microcirculation exhibits regional differences. Significant variability of function between ankle and dorsum of foot suggests that leg microcirculation is not uniform.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Vasa

ISSN

0301-1526

e-ISSN

—

Svazek periodika

44

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

8

Strana od-do

458-465

Kód UT WoS článku

000365042900007

EID výsledku v databázi Scopus

—