Novel electrospun gelatin/oxycellulose nanofibers as a suitable platform for lung disease modeling

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F16%3A00065055" target="_blank" >RIV/00159816:_____/16:00065055 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14310/16:00089927 RIV/00216305:26310/16:PU119314

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.msec.2016.05.059" target="_blank" >http://dx.doi.org/10.1016/j.msec.2016.05.059</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.msec.2016.05.059" target="_blank" >10.1016/j.msec.2016.05.059</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Novel electrospun gelatin/oxycellulose nanofibers as a suitable platform for lung disease modeling

Popis výsledku v původním jazyce

Novel hydrolytically stable gelatin nanofibers modified with sodium or calcium salt of oxycellulose were prepared by electrospinningmethod. The unique inhibitory effect of these nanofibers against Escherichia coli bacteria was examined by luminometric method. Biocompatibility of these gelatin/oxycellulose nanofibers with eukaryotic cells was tested using human lung adenocarcinoma cell line NCI-H441. Cells firmly adhered to nanofiber surface, as determined by scanning electron microscopy, and no signs of cell dying were detected by fluorescent live/ dead assay. We propose that the newly developed gelatin/oxycellulose nanofibers could be used as promising scaffold for lung disease modeling and anti-cancer drug testing

Název v anglickém jazyce

Novel electrospun gelatin/oxycellulose nanofibers as a suitable platform for lung disease modeling

Popis výsledku anglicky

Novel hydrolytically stable gelatin nanofibers modified with sodium or calcium salt of oxycellulose were prepared by electrospinningmethod. The unique inhibitory effect of these nanofibers against Escherichia coli bacteria was examined by luminometric method. Biocompatibility of these gelatin/oxycellulose nanofibers with eukaryotic cells was tested using human lung adenocarcinoma cell line NCI-H441. Cells firmly adhered to nanofiber surface, as determined by scanning electron microscopy, and no signs of cell dying were detected by fluorescent live/ dead assay. We propose that the newly developed gelatin/oxycellulose nanofibers could be used as promising scaffold for lung disease modeling and anti-cancer drug testing

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EI - Biotechnologie a bionika

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Materials Science &amp; Engineering C-Materials for Biological

ISSN

0928-4931

e-ISSN

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Svazek periodika

67

Číslo periodika v rámci svazku

OCT

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

9

Strana od-do

493-501

Kód UT WoS článku

000378952800056

EID výsledku v databázi Scopus

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