Cox proportional hazard model and its application to data analysis of failure of endodontic equipment

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F17%3A00067626" target="_blank" >RIV/00159816:_____/17:00067626 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14310/17:00095503 RIV/00216208:11110/17:10374530

Výsledek na webu

<a href="http://dx.doi.org/10.5507/bp.2016.063" target="_blank" >http://dx.doi.org/10.5507/bp.2016.063</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2016.063" target="_blank" >10.5507/bp.2016.063</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Cox proportional hazard model and its application to data analysis of failure of endodontic equipment

Popis výsledku v původním jazyce

Background and Aims. A very common statistical method used in statistical analysis of medical data is the Cox proportional hazard model (Cox model). The aim of this paper is to describe statistical data analysis as a process beginning with data management, followed by statistical coding and statistical analysis, including survival analysis and the Cox model, and finishing with the interpretation of results. The methods are applied to the data from stomatology - the influence of selected variables on the fracture of endodontic equipment. Statistical analyses were performed in R. Methods. Exploratory analysis and visualization methods are firstly presented. The survival analysis methods of KaplanMeier&apos;s product limit estimate, estimate of the cumulative hazard function, and Nair&apos;s 95% confidence bands are then calculated. Finally, the conditional hazard is modelled with the Cox model where regression parameters are tested with the Wald test and the proportionality of hazard with the Schoenfeld test. Results. In the Cox model, covariates influencing the fracture of endodontic equipment, the radius of the dental canal, the size and brand of the endodontic equipment (Mtwo, ProTaper, Revo-S, and Wizard Navigator) were used. The regression parameters of the radius of the dental canal and endodontic equipment size proved to be statistically significant. Compared to the reference brand Mtwo endodontic equipment, the regression parameters of the ProTaper and Revo-S drills proved to be statistically significant. Conclusions. Fracturing endodontic equipment during a root canal treatment often leads to undesirable resting of the tool in the root canal of the patient&apos;s tooth, which can lead to less successful endodontic treatment and thus less satisfactory prognosis.

Název v anglickém jazyce

Cox proportional hazard model and its application to data analysis of failure of endodontic equipment

Popis výsledku anglicky

Background and Aims. A very common statistical method used in statistical analysis of medical data is the Cox proportional hazard model (Cox model). The aim of this paper is to describe statistical data analysis as a process beginning with data management, followed by statistical coding and statistical analysis, including survival analysis and the Cox model, and finishing with the interpretation of results. The methods are applied to the data from stomatology - the influence of selected variables on the fracture of endodontic equipment. Statistical analyses were performed in R. Methods. Exploratory analysis and visualization methods are firstly presented. The survival analysis methods of KaplanMeier&apos;s product limit estimate, estimate of the cumulative hazard function, and Nair&apos;s 95% confidence bands are then calculated. Finally, the conditional hazard is modelled with the Cox model where regression parameters are tested with the Wald test and the proportionality of hazard with the Schoenfeld test. Results. In the Cox model, covariates influencing the fracture of endodontic equipment, the radius of the dental canal, the size and brand of the endodontic equipment (Mtwo, ProTaper, Revo-S, and Wizard Navigator) were used. The regression parameters of the radius of the dental canal and endodontic equipment size proved to be statistically significant. Compared to the reference brand Mtwo endodontic equipment, the regression parameters of the ProTaper and Revo-S drills proved to be statistically significant. Conclusions. Fracturing endodontic equipment during a root canal treatment often leads to undesirable resting of the tool in the root canal of the patient&apos;s tooth, which can lead to less successful endodontic treatment and thus less satisfactory prognosis.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20602 - Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

BIOMEDICAL PAPERS-OLOMOUC

ISSN

1213-8118

e-ISSN

—

Svazek periodika

161

Číslo periodika v rámci svazku

S1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

11

Strana od-do

"S1"-"S11"

Kód UT WoS článku

000428945000001

EID výsledku v databázi Scopus

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