Tension-based abdominal aortic aneurysm rupture risk assessment improves its accuracy and reduces the time of analysis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F24%3A00081069" target="_blank" >RIV/00159816:_____/24:00081069 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/24:00137418 RIV/61989100:27230/24:10256277

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/abs/pii/S0021929024004068" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S0021929024004068</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jbiomech.2024.112328" target="_blank" >10.1016/j.jbiomech.2024.112328</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Tension-based abdominal aortic aneurysm rupture risk assessment improves its accuracy and reduces the time of analysis

Popis výsledku v původním jazyce

The biomechanical rupture risk assessment (BRRA) of abdominal aortic aneurysms (AAA) has higher sensitivity than maximal diameter criterion (DSEX) but its estimation is time-consuming and relies on an uncertain estimation of wall thickness. The aim of this study is to test tension-based criterion in the BRRA of AAA which removes the necessity of wall thickness measurement and should be faster. For that, we retrospectively analyzed 99 patients with intact AAA (25 females). Nineteen of them experienced a rupture later. BRRA was performed with wall tension PRRIT as a primary criterion. The ability of criterion to separate intact and ruptured AAAs at 1,3,6,9 and 12 months was estimated. Next, the receiver operating characteristics and the percentage of true negative cases for a different time to an outcome were estimated. Finally, the computational time was recorded. The results were compared to stress-based criterion PRRI and D-SEX which served as a reference. All three criterions were able to discriminate between intact and ruptured AAAs up to 9 months (p &lt; 0.05) while none of them could do for a 12 month prediction. PRRIT exhibited a significantly higher percentage of true negatives for 12 and 9 month predictions (45 % and 20 % respectively) and similar to other criteria for other prediction times. The mean computational time for estimating PRRIT was 19 h per patient compared to 67 h for PRRI. The tension- based BRRA of AAA leads to better outcomes for a 9 and 12 month prediction while the computational time drops by more than 70 % compared to PRRI.

Název v anglickém jazyce

Tension-based abdominal aortic aneurysm rupture risk assessment improves its accuracy and reduces the time of analysis

Popis výsledku anglicky

The biomechanical rupture risk assessment (BRRA) of abdominal aortic aneurysms (AAA) has higher sensitivity than maximal diameter criterion (DSEX) but its estimation is time-consuming and relies on an uncertain estimation of wall thickness. The aim of this study is to test tension-based criterion in the BRRA of AAA which removes the necessity of wall thickness measurement and should be faster. For that, we retrospectively analyzed 99 patients with intact AAA (25 females). Nineteen of them experienced a rupture later. BRRA was performed with wall tension PRRIT as a primary criterion. The ability of criterion to separate intact and ruptured AAAs at 1,3,6,9 and 12 months was estimated. Next, the receiver operating characteristics and the percentage of true negative cases for a different time to an outcome were estimated. Finally, the computational time was recorded. The results were compared to stress-based criterion PRRI and D-SEX which served as a reference. All three criterions were able to discriminate between intact and ruptured AAAs up to 9 months (p &lt; 0.05) while none of them could do for a 12 month prediction. PRRIT exhibited a significantly higher percentage of true negatives for 12 and 9 month predictions (45 % and 20 % respectively) and similar to other criteria for other prediction times. The mean computational time for estimating PRRIT was 19 h per patient compared to 67 h for PRRI. The tension- based BRRA of AAA leads to better outcomes for a 9 and 12 month prediction while the computational time drops by more than 70 % compared to PRRI.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30100 - Basic medicine

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

JOURNAL OF BIOMECHANICS

ISSN

0021-9290

e-ISSN

1873-2380

Svazek periodika

176

Číslo periodika v rámci svazku

NOV 2024

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

8

Strana od-do

112328

Kód UT WoS článku

001331130600001

EID výsledku v databázi Scopus

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