Computed tomography-guided percutaneous biopsy in diagnosis of suspected metastatic renal cell carcinoma: which location is the most suitable?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F24%3A10490981" target="_blank" >RIV/00179906:_____/24:10490981 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11150/24:10490981

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=e1ypm-M7_n" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=e1ypm-M7_n</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.20452/wiitm.2024.17894" target="_blank" >10.20452/wiitm.2024.17894</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Computed tomography-guided percutaneous biopsy in diagnosis of suspected metastatic renal cell carcinoma: which location is the most suitable?

Popis výsledku v původním jazyce

Introduction: Systemic targeted therapy options are commonly used in patients with metastatic renal cell carcinoma (mRCC). Histological verification is crucial for treatment of mRCC. Aim: Our aim was to evaluate an optimal location for percutaneous computed tomography-guided biopsy in a diagnosis of suspected mRCC. Materials and methods: A total of 138 percutaneous biopsies for tumors ranging from 21 to 133 mm in diameter (median, 72 mm) were carried out in 134 patients with suspected mRCC over a 5-year period. The biopsy location was variable, with kidney biopsy performed in 77 cases (55.8%), and other localizations (retroperitoneum, peritoneal cavity, liver, pelvis, pleural space, lung, mediastinum, chest or abdominal wall, and pancreas) in 61 cases (44.2%). Results: As many as 288 biopsies (97.1%), yielded true-positive results, and 4 procedures (2.9%) yielded histologically false-negative results that required confirmation through extended rebiopsy. RCC was the most common individual diagnosis (85.5%), with non-RCC histology verified in 14.5% of cases. In total, 32 complications (23.2%) were confirmed, 2 of which were pneumothoraces, 29 were minor bleeding that needed only conservative management, and 1 case required angiography and embolization for hemorrhage treatment. While no significant relationship between the biopsy success and lesion localization (renal vs other) was found (P = 0.13), the relationship between complication rate and biopsy localization (renal vs other) was significant (P = 0.01). Conclusions: Lesion localization (renal vs other) was not relevant to histological accuracy of the biopsies performed in patients with suspected mRCC. However, the biopsies of lesions outside the kidney had a lower complication rate.

Název v anglickém jazyce

Computed tomography-guided percutaneous biopsy in diagnosis of suspected metastatic renal cell carcinoma: which location is the most suitable?

Popis výsledku anglicky

Introduction: Systemic targeted therapy options are commonly used in patients with metastatic renal cell carcinoma (mRCC). Histological verification is crucial for treatment of mRCC. Aim: Our aim was to evaluate an optimal location for percutaneous computed tomography-guided biopsy in a diagnosis of suspected mRCC. Materials and methods: A total of 138 percutaneous biopsies for tumors ranging from 21 to 133 mm in diameter (median, 72 mm) were carried out in 134 patients with suspected mRCC over a 5-year period. The biopsy location was variable, with kidney biopsy performed in 77 cases (55.8%), and other localizations (retroperitoneum, peritoneal cavity, liver, pelvis, pleural space, lung, mediastinum, chest or abdominal wall, and pancreas) in 61 cases (44.2%). Results: As many as 288 biopsies (97.1%), yielded true-positive results, and 4 procedures (2.9%) yielded histologically false-negative results that required confirmation through extended rebiopsy. RCC was the most common individual diagnosis (85.5%), with non-RCC histology verified in 14.5% of cases. In total, 32 complications (23.2%) were confirmed, 2 of which were pneumothoraces, 29 were minor bleeding that needed only conservative management, and 1 case required angiography and embolization for hemorrhage treatment. While no significant relationship between the biopsy success and lesion localization (renal vs other) was found (P = 0.13), the relationship between complication rate and biopsy localization (renal vs other) was significant (P = 0.01). Conclusions: Lesion localization (renal vs other) was not relevant to histological accuracy of the biopsies performed in patients with suspected mRCC. However, the biopsies of lesions outside the kidney had a lower complication rate.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30224 - Radiology, nuclear medicine and medical imaging

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Videosurgery and Other Miniinvasive Techniques

ISSN

1895-4588

e-ISSN

2299-0054

Svazek periodika

19

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

9

Strana od-do

361-369

Kód UT WoS článku

001414764400011

EID výsledku v databázi Scopus

2-s2.0-85215630209