Decrease of muscle strength in vascular access hand due to silent ischaemia

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10383510" target="_blank" >RIV/00216208:11110/18:10383510 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064165:_____/18:10383510

Výsledek na webu

<a href="https://doi.org/10.1177/1129729818763287" target="_blank" >https://doi.org/10.1177/1129729818763287</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1177/1129729818763287" target="_blank" >10.1177/1129729818763287</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Decrease of muscle strength in vascular access hand due to silent ischaemia

Popis výsledku v původním jazyce

Background: Creation of vascular access leads to considerable local haemodynamic changes with decreased hand perfusion. Distal limb tissues then represent a model of hand ischaemia effect on muscles. The aim of our study was to investigate how the presence of vascular access influences the hand muscle strength in end-stage renal disease patients. Methods: We included 52 chronically haemodialysed patients with upper limb access without clinical signs of hand ischaemia. Muscle strength was evaluated by dynamometry. Finger pressure was measured on the second and fourth fingers and averaged for further analysis. Thenar tissue oxygenation (rSO(2)) was analysed using near-infrared spectroscopy. All examinations were performed in both the hands. Basic laboratory analysis was added. Data were processed with unpaired t-test and correlation analysis. Results: Hands with dialysis access had lower values of handgrip strength (54.2 +/- 29.1 lbs vs 48.6 +/- 23.4 lbs, p = 0.0006), systolic finger pressure (127.1 +/- 32.0 mmHg vs 101.4 +/- 31.6 mmHg, p &lt; 10(-8)) and of thenar rSO(2) (45.8% +/- 12.9% vs 42.5% +/- 13.3%, p = 0.002). Muscle strength (handgrip) was directly related to the thenar oxygenation (r = 0.36; p = 0.014) and to the finger systolic pressure (r = 0.38; p = 0.007) on the access extremity. On the extremity without dialysis access, handgrip strength was inversely related to patient&apos;s age (r = -0.41, p = 0.003), dialysis vintage (r = -0.32, p = 0.02) and red cell distribution width (r = -0.37, p = 0.01). Conclusion: The presence of dialysis access leads to the decrease of finger pressure, oxygenation, and also muscle strength even in the absence of clinically overt hand ischaemia. All these parameters are interrelated. This study underlines the consequences of inadequate muscle perfusion.

Název v anglickém jazyce

Decrease of muscle strength in vascular access hand due to silent ischaemia

Popis výsledku anglicky

Background: Creation of vascular access leads to considerable local haemodynamic changes with decreased hand perfusion. Distal limb tissues then represent a model of hand ischaemia effect on muscles. The aim of our study was to investigate how the presence of vascular access influences the hand muscle strength in end-stage renal disease patients. Methods: We included 52 chronically haemodialysed patients with upper limb access without clinical signs of hand ischaemia. Muscle strength was evaluated by dynamometry. Finger pressure was measured on the second and fourth fingers and averaged for further analysis. Thenar tissue oxygenation (rSO(2)) was analysed using near-infrared spectroscopy. All examinations were performed in both the hands. Basic laboratory analysis was added. Data were processed with unpaired t-test and correlation analysis. Results: Hands with dialysis access had lower values of handgrip strength (54.2 +/- 29.1 lbs vs 48.6 +/- 23.4 lbs, p = 0.0006), systolic finger pressure (127.1 +/- 32.0 mmHg vs 101.4 +/- 31.6 mmHg, p &lt; 10(-8)) and of thenar rSO(2) (45.8% +/- 12.9% vs 42.5% +/- 13.3%, p = 0.002). Muscle strength (handgrip) was directly related to the thenar oxygenation (r = 0.36; p = 0.014) and to the finger systolic pressure (r = 0.38; p = 0.007) on the access extremity. On the extremity without dialysis access, handgrip strength was inversely related to patient&apos;s age (r = -0.41, p = 0.003), dialysis vintage (r = -0.32, p = 0.02) and red cell distribution width (r = -0.37, p = 0.01). Conclusion: The presence of dialysis access leads to the decrease of finger pressure, oxygenation, and also muscle strength even in the absence of clinically overt hand ischaemia. All these parameters are interrelated. This study underlines the consequences of inadequate muscle perfusion.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

<a href="/cs/project/NV17-31796A" target="_blank" >NV17-31796A: Tkáňová hypoxie u pacientů s chronickým onemocněním ledvin – metabolické a hemodynamické souvislosti</a><br>

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

The Journal of Vascular Access

ISSN

1129-7298

e-ISSN

—

Svazek periodika

19

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

IT - Italská republika

Počet stran výsledku

5

Strana od-do

573-577

Kód UT WoS článku

000450363300010

EID výsledku v databázi Scopus

2-s2.0-85052607297