Telomeres and telomerase activity in the human placenta

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F20%3A10408760" target="_blank" >RIV/00216208:11110/20:10408760 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.intechopen.com/online-first/telomeres-and-telomerase-activity-in-the-human-placenta" target="_blank" >https://www.intechopen.com/online-first/telomeres-and-telomerase-activity-in-the-human-placenta</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5772/intechopen.86327" target="_blank" >10.5772/intechopen.86327</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Telomeres and telomerase activity in the human placenta

Popis výsledku v původním jazyce

Placenta is a transient organ ensuring the intrauterine development of the individual. To meet fetal requirements, rapid and continuous cell proliferation enlarges the areas of tissues maintaining maternofetal transport. The cell division in placenta is accompanied with shortening of telomeres leading to cell senescence. Telomerase activity, on the other hand, ensures replication of telomeres and allows the organ to serve till the end of pregnancy. This balanced process may be negatively influenced by unfavorable circumstances. Here, we summarize available data on telomere length as well as telomerase activity in placentas from normal and complicated pregnancies; attention is also paid to the comparison of methods used in relevant studies.

Název v anglickém jazyce

Telomeres and telomerase activity in the human placenta

Popis výsledku anglicky

Placenta is a transient organ ensuring the intrauterine development of the individual. To meet fetal requirements, rapid and continuous cell proliferation enlarges the areas of tissues maintaining maternofetal transport. The cell division in placenta is accompanied with shortening of telomeres leading to cell senescence. Telomerase activity, on the other hand, ensures replication of telomeres and allows the organ to serve till the end of pregnancy. This balanced process may be negatively influenced by unfavorable circumstances. Here, we summarize available data on telomere length as well as telomerase activity in placentas from normal and complicated pregnancies; attention is also paid to the comparison of methods used in relevant studies.

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

10600 - Biological sciences

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Telomerase and non-Telomerase Mechanisms of Telomere Maintenance

ISBN

978-1-78984-574-7

Počet stran výsledku

20

Strana od-do

99-118

Počet stran knihy

118

Název nakladatele

IntechOpen

Místo vydání

London

Kód UT WoS kapitoly

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