Post-prandial endothelial dysfunction is ameliorated following weight loss in obese premenopausal women
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F11%3A00003205" target="_blank" >RIV/00216208:11120/11:00003205 - isvavai.cz</a>
Výsledek na webu
<a href="http://www.medscimonit.com/fulltxt.php?ICID=882048" target="_blank" >http://www.medscimonit.com/fulltxt.php?ICID=882048</a>
DOI - Digital Object Identifier
—
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Post-prandial endothelial dysfunction is ameliorated following weight loss in obese premenopausal women
Popis výsledku v původním jazyce
Endothelial dysfunction and postprandial hyperglycemia represent independent risk factors for cardiovascular diseases. Obesity is connected with endothelial impairments; however, it is unclear whether weight loss can modify endothelial function during the postprandial period. The aim of this study was to evaluate endothelial response (post-ischemic forearm blood flow, PIFBF) in a fasted state and following ingestion of 75 g glucose before and after very low caloric diet (VLCD). 40 obese premenopausal women (age 39.6- 7.8 years, BMI 34.3-3.2 kg/m2) participated in 4-week very low caloric diet (VLCD, 800 kcal/day). Before and after VLCD, the baseline blood flow and PIFBF were measured using a mercury strain gauge plethysmography in fasting state as wellas 1 hour after ingestion of 75 g glucose. Dietary intervention resulted in a 7% weight loss (p<0.05) and a decrease in insulin resistance index HOMA-IR (2.44-1.25 vs. 1.66-0.81, p<0.05). Before VLCD intervention, PIFBF following oral glu
Název v anglickém jazyce
Post-prandial endothelial dysfunction is ameliorated following weight loss in obese premenopausal women
Popis výsledku anglicky
Endothelial dysfunction and postprandial hyperglycemia represent independent risk factors for cardiovascular diseases. Obesity is connected with endothelial impairments; however, it is unclear whether weight loss can modify endothelial function during the postprandial period. The aim of this study was to evaluate endothelial response (post-ischemic forearm blood flow, PIFBF) in a fasted state and following ingestion of 75 g glucose before and after very low caloric diet (VLCD). 40 obese premenopausal women (age 39.6- 7.8 years, BMI 34.3-3.2 kg/m2) participated in 4-week very low caloric diet (VLCD, 800 kcal/day). Before and after VLCD, the baseline blood flow and PIFBF were measured using a mercury strain gauge plethysmography in fasting state as wellas 1 hour after ingestion of 75 g glucose. Dietary intervention resulted in a 7% weight loss (p<0.05) and a decrease in insulin resistance index HOMA-IR (2.44-1.25 vs. 1.66-0.81, p<0.05). Before VLCD intervention, PIFBF following oral glu
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FB - Endokrinologie, diabetologie, metabolismus, výživa
OECD FORD obor
—
Návaznosti výsledku
Projekt
—
Návaznosti
R - Projekt Ramcoveho programu EK
Ostatní
Rok uplatnění
2011
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Medical Science Monitor
ISSN
1234-1010
e-ISSN
—
Svazek periodika
17
Číslo periodika v rámci svazku
11
Stát vydavatele periodika
PL - Polská republika
Počet stran výsledku
6
Strana od-do
"CR634"-"CR639"
Kód UT WoS článku
000298036400020
EID výsledku v databázi Scopus
—