Two approaches to form antibacterial surface: Doping with bactericidal element and drug loading

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F15%3A10294530" target="_blank" >RIV/00216208:11130/15:10294530 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68378041:_____/15:00451300

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.apsusc.2014.12.119" target="_blank" >http://dx.doi.org/10.1016/j.apsusc.2014.12.119</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.apsusc.2014.12.119" target="_blank" >10.1016/j.apsusc.2014.12.119</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Two approaches to form antibacterial surface: Doping with bactericidal element and drug loading

Popis výsledku v původním jazyce

Two approaches (surface doping with bactericidal element and loading of antibiotic into specially formed surface microcontainers) to the fabrication of antibacterial yet biocompatible and bioactive surfaces are described. A network structure with square-shaped blind pores of 2.6 +/- 0.6 x 10(-3) mm(3) for drug loading was obtained by selective laser sintering (SLS). The SLS-fabricated samples were loaded with 0.03, 0.3, 2.4, and 4 mg/cm(2) of co-amoxiclav (amoxicillin and clavulanic acid). Ag-doped TiCaPCON films with 0.4, 1.2, and 4.0 at.% of Ag were obtained by co-sputtering of composite TiC0.5-Ca-3(PO4)(2) and metallic Ag targets. The surface structure of SLS-prepared samples and cross-sectional morphology of TiCaPCON-Ag films were studied by scanning electron microscopy. The through-thickness of Ag distribution in the TiCaPCON-Ag films was obtained by glow discharge optical emission spectroscopy. The kinetics of Ag ion release in normal saline solution was studied using inductively

Název v anglickém jazyce

Two approaches to form antibacterial surface: Doping with bactericidal element and drug loading

Popis výsledku anglicky

Two approaches (surface doping with bactericidal element and loading of antibiotic into specially formed surface microcontainers) to the fabrication of antibacterial yet biocompatible and bioactive surfaces are described. A network structure with square-shaped blind pores of 2.6 +/- 0.6 x 10(-3) mm(3) for drug loading was obtained by selective laser sintering (SLS). The SLS-fabricated samples were loaded with 0.03, 0.3, 2.4, and 4 mg/cm(2) of co-amoxiclav (amoxicillin and clavulanic acid). Ag-doped TiCaPCON films with 0.4, 1.2, and 4.0 at.% of Ag were obtained by co-sputtering of composite TiC0.5-Ca-3(PO4)(2) and metallic Ag targets. The surface structure of SLS-prepared samples and cross-sectional morphology of TiCaPCON-Ag films were studied by scanning electron microscopy. The through-thickness of Ag distribution in the TiCaPCON-Ag films was obtained by glow discharge optical emission spectroscopy. The kinetics of Ag ion release in normal saline solution was studied using inductively

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

BO - Biofyzika

OECD FORD obor

—

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Applied Surface Science

ISSN

0169-4332

e-ISSN

—

Svazek periodika

330

Číslo periodika v rámci svazku

březen

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

12

Strana od-do

339-350

Kód UT WoS článku

000349617400042

EID výsledku v databázi Scopus

2-s2.0-84924085406