Olfactory identification in amnestic and non-amnestic mild cognitive impairment and its neuropsychological correlates

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F15%3A10294532" target="_blank" >RIV/00216208:11130/15:10294532 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00159816:_____/15:00061633 RIV/00064203:_____/15:10294532

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.jns.2015.01.014" target="_blank" >http://dx.doi.org/10.1016/j.jns.2015.01.014</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jns.2015.01.014" target="_blank" >10.1016/j.jns.2015.01.014</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Olfactory identification in amnestic and non-amnestic mild cognitive impairment and its neuropsychological correlates

Popis výsledku v původním jazyce

Background: Olfactory identification impairment in amnestic mild cognitive impairment (aMCI) patients is well documented and considered to be caused by underlying Alzheimer's disease (AD) pathology, contrasting with less clear evidence in non-amnestic MCI (naMCI). The aim was to (a) compare the degree of olfactory identification dysfunction in aMCI, naMCI, controls and mild AD dementia and (b) assess the relation between olfactory identification and cognitive performance in aMCI compared to naMCI. Methods: 75 patients with aMCI and 32 with naMCI, 26 patients with mild AD and 27 controls underwent the multiple choice olfactory identification Motol Hospital Smell Test with 18 different odors together with a comprehensive neuropsychological examination. Results: Controlling for age and gender, patients with aMCI and naMCI did not differ significantly in olfactory identification and both performed significantly worse than controls (p < 0.001), albeit also better than patients with mild AD

Název v anglickém jazyce

Olfactory identification in amnestic and non-amnestic mild cognitive impairment and its neuropsychological correlates

Popis výsledku anglicky

Background: Olfactory identification impairment in amnestic mild cognitive impairment (aMCI) patients is well documented and considered to be caused by underlying Alzheimer's disease (AD) pathology, contrasting with less clear evidence in non-amnestic MCI (naMCI). The aim was to (a) compare the degree of olfactory identification dysfunction in aMCI, naMCI, controls and mild AD dementia and (b) assess the relation between olfactory identification and cognitive performance in aMCI compared to naMCI. Methods: 75 patients with aMCI and 32 with naMCI, 26 patients with mild AD and 27 controls underwent the multiple choice olfactory identification Motol Hospital Smell Test with 18 different odors together with a comprehensive neuropsychological examination. Results: Controlling for age and gender, patients with aMCI and naMCI did not differ significantly in olfactory identification and both performed significantly worse than controls (p < 0.001), albeit also better than patients with mild AD

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

—

Projekt

<a href="/cs/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: Fakultní nemocnice u sv. Anny v Brně - Mezinárodní centrum klinického výzkumu (FNUSA - ICRC)</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of the Neurological Sciences

ISSN

0022-510X

e-ISSN

—

Svazek periodika

349

Číslo periodika v rámci svazku

1-2

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

6

Strana od-do

179-184

Kód UT WoS článku

000350516200030

EID výsledku v databázi Scopus

2-s2.0-84923942328