Cognition, dependence and opioids in patients with chronic non-cancer pains

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F17%3A10374410" target="_blank" >RIV/00216208:11130/17:10374410 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064203:_____/17:10374410

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Cognition, dependence and opioids in patients with chronic non-cancer pains

Popis výsledku v původním jazyce

In the field of chronic pain therapy, considerable concerns about dependence to opioids occur in patients with chronic non-cancer pain, sometimes even taking the form of opiate phobia (opioidphobia). For this reason, current studies of this topic, drawing from neuro-psycho-pharmacological research, seek to develop a conceptual framework of dependence development in patients suffering from chronic pain. The addictive use of opioids is understood as a result of a cycle that starts with chronic pain and negative feelings, and is reinforced by opiate-dopamine interaction leading to attention hypervigilance to pain and stimuli associated with medication, a dysfunctional connection between cognitive control networks in the brain and the allostatic dysregulation of systems that respond to stress and reward. Not only the screening model of determining dependence, but some multimodal therapeutic approaches are also introduced as a potentially efficient approach to breaking dependence and facilitating the treatment of chronic non-cancer pain and dependence. The chapter also describes specific neuropsychological and cognitive deficits developed in patients with opioid dependence; in the literature, these deficits are not distinguished with respect to the population of patients with dependence and patients with chronic non-cancer pain treated with opioids. The aim of this chapter is to describe how opioids interact with cognitive, affective and psychological factors that are involved in chronic pain, and with behaviour related to dependence. Finally, the clinical consequences of this model for psychotherapeutic treatment of patients with chronic non-cancer pain are described.

Název v anglickém jazyce

Cognition, dependence and opioids in patients with chronic non-cancer pains

Popis výsledku anglicky

In the field of chronic pain therapy, considerable concerns about dependence to opioids occur in patients with chronic non-cancer pain, sometimes even taking the form of opiate phobia (opioidphobia). For this reason, current studies of this topic, drawing from neuro-psycho-pharmacological research, seek to develop a conceptual framework of dependence development in patients suffering from chronic pain. The addictive use of opioids is understood as a result of a cycle that starts with chronic pain and negative feelings, and is reinforced by opiate-dopamine interaction leading to attention hypervigilance to pain and stimuli associated with medication, a dysfunctional connection between cognitive control networks in the brain and the allostatic dysregulation of systems that respond to stress and reward. Not only the screening model of determining dependence, but some multimodal therapeutic approaches are also introduced as a potentially efficient approach to breaking dependence and facilitating the treatment of chronic non-cancer pain and dependence. The chapter also describes specific neuropsychological and cognitive deficits developed in patients with opioid dependence; in the literature, these deficits are not distinguished with respect to the population of patients with dependence and patients with chronic non-cancer pain treated with opioids. The aim of this chapter is to describe how opioids interact with cognitive, affective and psychological factors that are involved in chronic pain, and with behaviour related to dependence. Finally, the clinical consequences of this model for psychotherapeutic treatment of patients with chronic non-cancer pain are described.

Druh

C - Kapitola v odborné knize

CEP obor

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OECD FORD obor

50101 - Psychology (including human - machine relations)

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Pain: Management, Issues and Controversies

ISBN

978-1-5361-2227-5

Počet stran výsledku

23

Strana od-do

169-191

Počet stran knihy

367

Název nakladatele

Nova Science Publishers, Inc.

Místo vydání

New York

Kód UT WoS kapitoly

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