Prevalence of underweight, overweight, and obesity in children and adolescents with type 1 diabetes: Data from the international SWEET registry

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F18%3A10381323" target="_blank" >RIV/00216208:11130/18:10381323 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064203:_____/18:10381323

Výsledek na webu

<a href="https://doi.org/10.1111/pedi.12730" target="_blank" >https://doi.org/10.1111/pedi.12730</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/pedi.12730" target="_blank" >10.1111/pedi.12730</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Prevalence of underweight, overweight, and obesity in children and adolescents with type 1 diabetes: Data from the international SWEET registry

Popis výsledku v původním jazyce

Objective: To assess the prevalence of underweight (UW), overweight (OW), and obesity in children and adolescents with type 1 diabetes (T1D). Methods: An international cross-sectional study including 23026 T1D children (2-18 years, duration of diabetes &gt;= 1 year)participating in the SWEET prospective, multicenter diabetes registry. Body mass index SD score (BMI-SDS) was calculated using the World Health Organization BMI charts. Children were categorized as UW (BMI-SDS&lt;-2SD), OW (+1SD &lt; BMI-SDS &lt;= +2SD), and obese (OB) (BMI-SDS &gt; +2SD). Hierarchic regression models were applied with adjustment for sex, age, and duration of diabetes. Results: The prevalence of UW, OW, and obesity was: 1.4%, 22.3%, and 7.3% in males and 0.6%, 27.2%, and 6.8% in females. Adjusted BMI-SDS was significantly higher in females than in males (meanSEM: 0.54 +/- 0.05 vs 0.40 +/- 0.05, P &lt; 0.0001). In males, BMI-SDS significantly decreased by age (P &lt; 0.0001) in the first three age categories 0.61 +/- 0.06 (2 to &lt;10 years), 0.47 +/- 0.06 (10 to &lt;13 years), 0.34 +/- 0.05 (13 to &lt;16 years). In females, BMI-SDS showed a U-shaped distribution by age (P &lt; 0.0001): 0.54 +/- 0.04 (2 to &lt;10years), 0.39 +/- 0.04 (10 to &lt;13 years), 0.55 +/- 0.04 (13 to &lt;16 years). BMI-SDS increased by diabetes duration (&lt;2years: 0.38 +/- 0.05, 2 to &lt;5 years: 0.44 +/- 0.05, and 5years: 0.50 +/- 0.05, P &lt; 0.0001). Treatment modality did not affect BMI-SDS. Adjusted HbA1c was significantly higher in females than in males (8.20% +/- 0.10% vs 8.06% +/- 0.10%, P &lt; 0.0001). In both genders, the association between HbA1c and BMI-SDS was U-shaped with the highest HbA1c in the UW and obesity groups. Conclusions: The high rate of OW and obesity (31.8%) emphasize the need for developing further strategies to prevent and treat excess fat accumulation in T1D.

Název v anglickém jazyce

Prevalence of underweight, overweight, and obesity in children and adolescents with type 1 diabetes: Data from the international SWEET registry

Popis výsledku anglicky

Objective: To assess the prevalence of underweight (UW), overweight (OW), and obesity in children and adolescents with type 1 diabetes (T1D). Methods: An international cross-sectional study including 23026 T1D children (2-18 years, duration of diabetes &gt;= 1 year)participating in the SWEET prospective, multicenter diabetes registry. Body mass index SD score (BMI-SDS) was calculated using the World Health Organization BMI charts. Children were categorized as UW (BMI-SDS&lt;-2SD), OW (+1SD &lt; BMI-SDS &lt;= +2SD), and obese (OB) (BMI-SDS &gt; +2SD). Hierarchic regression models were applied with adjustment for sex, age, and duration of diabetes. Results: The prevalence of UW, OW, and obesity was: 1.4%, 22.3%, and 7.3% in males and 0.6%, 27.2%, and 6.8% in females. Adjusted BMI-SDS was significantly higher in females than in males (meanSEM: 0.54 +/- 0.05 vs 0.40 +/- 0.05, P &lt; 0.0001). In males, BMI-SDS significantly decreased by age (P &lt; 0.0001) in the first three age categories 0.61 +/- 0.06 (2 to &lt;10 years), 0.47 +/- 0.06 (10 to &lt;13 years), 0.34 +/- 0.05 (13 to &lt;16 years). In females, BMI-SDS showed a U-shaped distribution by age (P &lt; 0.0001): 0.54 +/- 0.04 (2 to &lt;10years), 0.39 +/- 0.04 (10 to &lt;13 years), 0.55 +/- 0.04 (13 to &lt;16 years). BMI-SDS increased by diabetes duration (&lt;2years: 0.38 +/- 0.05, 2 to &lt;5 years: 0.44 +/- 0.05, and 5years: 0.50 +/- 0.05, P &lt; 0.0001). Treatment modality did not affect BMI-SDS. Adjusted HbA1c was significantly higher in females than in males (8.20% +/- 0.10% vs 8.06% +/- 0.10%, P &lt; 0.0001). In both genders, the association between HbA1c and BMI-SDS was U-shaped with the highest HbA1c in the UW and obesity groups. Conclusions: The high rate of OW and obesity (31.8%) emphasize the need for developing further strategies to prevent and treat excess fat accumulation in T1D.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30202 - Endocrinology and metabolism (including diabetes, hormones)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Pediatric Diabetes

ISSN

1399-543X

e-ISSN

—

Svazek periodika

19

Číslo periodika v rámci svazku

7

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

10

Strana od-do

1211-1220

Kód UT WoS článku

000446564900010

EID výsledku v databázi Scopus

2-s2.0-85052664720