Development of ZnO NRs-rGO Low-Impedance Electrodes for Astrocyte Cell Signal Recording

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F23%3A10472944" target="_blank" >RIV/00216208:11130/23:10472944 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1109/SENSORS56945.2023.10325202" target="_blank" >http://dx.doi.org/10.1109/SENSORS56945.2023.10325202</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1109/SENSORS56945.2023.10325202" target="_blank" >10.1109/SENSORS56945.2023.10325202</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Development of ZnO NRs-rGO Low-Impedance Electrodes for Astrocyte Cell Signal Recording

Popis výsledku v původním jazyce

The study of brain signals is now going beyond the traditional study of electrogenic neuronal cells. Currently, it has been demonstrated that even non-electrogenic cells present in the brain such as astrocytes can concur to physiological brain communication. Indeed, in the so-called tripartite synapse model, the small extracellular ionic currents, exchanged between astrocytes and neurons, are of interest to deeply understand local processes of transfer and storage of information. Current electrodes are limited by high-impedance and low selectivity and cannot efficiently detect signals in the range of few uV. A method to overcome these issues is the use of nanostructured glio-friendly electrodes for the development of low-impedance recording devices. In this work we present a new nanostructured bio-junction where Zinc Oxide nanorods can be implemented to improve impedance properties, while the addition of reduced Graphene Oxide is crucial to increase astrocyte adhesion and differentiation.

Název v anglickém jazyce

Development of ZnO NRs-rGO Low-Impedance Electrodes for Astrocyte Cell Signal Recording

Popis výsledku anglicky

The study of brain signals is now going beyond the traditional study of electrogenic neuronal cells. Currently, it has been demonstrated that even non-electrogenic cells present in the brain such as astrocytes can concur to physiological brain communication. Indeed, in the so-called tripartite synapse model, the small extracellular ionic currents, exchanged between astrocytes and neurons, are of interest to deeply understand local processes of transfer and storage of information. Current electrodes are limited by high-impedance and low selectivity and cannot efficiently detect signals in the range of few uV. A method to overcome these issues is the use of nanostructured glio-friendly electrodes for the development of low-impedance recording devices. In this work we present a new nanostructured bio-junction where Zinc Oxide nanorods can be implemented to improve impedance properties, while the addition of reduced Graphene Oxide is crucial to increase astrocyte adhesion and differentiation.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

IEEE Sensors 2023 - Conference Proceedings

ISBN

979-8-3503-0387-2

ISSN

1930-0395

e-ISSN

2168-9229

Počet stran výsledku

4

Strana od-do

—

Název nakladatele

IEEE

Místo vydání

Piscataway, USA

Místo konání akce

Vídeň, Rakousko

Datum konání akce

29. 10. 2023

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

001116741300351