Histology of abdominal incisions in rabbit - in vivo experiment with incorporation of artificial meshes

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F15%3A10298040" target="_blank" >RIV/00216208:11140/15:10298040 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Histology of abdominal incisions in rabbit - in vivo experiment with incorporation of artificial meshes

Popis výsledku v původním jazyce

Our aim was to analyze the tissue reaction to incorporation of artificial tissue-engineered mesh (PCL nanofibres) in rabbit after 6 weeks of regeneration. From histological point of view, the incision supported with scaffolds formed a more regularly arranged wound with more type I collagen than the incisions healing spontaneously without the scaffold support. The scaffolds were well integrated with the granular and dense connective tissue. The inflammatory cells found adjacent to the scaffolds formed nofoci weakening the wall. The scaffolds probably affected also formation of blood vessels in the adjacent region without incision, which resulted in a greater fraction of myofibroblasts in aminals with scaffolds when compared to animals without scaffolds.

Název v anglickém jazyce

Histology of abdominal incisions in rabbit - in vivo experiment with incorporation of artificial meshes

Popis výsledku anglicky

Our aim was to analyze the tissue reaction to incorporation of artificial tissue-engineered mesh (PCL nanofibres) in rabbit after 6 weeks of regeneration. From histological point of view, the incision supported with scaffolds formed a more regularly arranged wound with more type I collagen than the incisions healing spontaneously without the scaffold support. The scaffolds were well integrated with the granular and dense connective tissue. The inflammatory cells found adjacent to the scaffolds formed nofoci weakening the wall. The scaffolds probably affected also formation of blood vessels in the adjacent region without incision, which resulted in a greater fraction of myofibroblasts in aminals with scaffolds when compared to animals without scaffolds.

Druh

V_souhrn - Souhrnná výzkumná zpráva

CEP obor

EA - Morfologické obory a cytologie

OECD FORD obor

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Projekt

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Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2015

Kód důvěrnosti údajů

C - Předmět řešení projektu podléhá obchodnímu tajemství (§ 504 Občanského zákoníku), ale název projektu, cíle projektu a u ukončeného nebo zastaveného projektu zhodnocení výsledku řešení projektu (údaje P03, P04, P15, P19, P29, PN8) dodané do CEP, jsou upraveny tak, aby byly zveřejnitelné.

Počet stran výsledku

16

Místo vydání

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Název nakladatele resp. objednatele

Technická univerzita v Liberci

Verze

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