Transcranial sonography and I-123-FP-CIT single photon emission computed tomography in movement disorders

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F14%3A10281773" target="_blank" >RIV/00216208:11150/14:10281773 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.ultrasmedbio.2014.05.014" target="_blank" >http://dx.doi.org/10.1016/j.ultrasmedbio.2014.05.014</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ultrasmedbio.2014.05.014" target="_blank" >10.1016/j.ultrasmedbio.2014.05.014</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Transcranial sonography and I-123-FP-CIT single photon emission computed tomography in movement disorders

Popis výsledku v původním jazyce

Diagnosis of Parkinson's disease (PD) can be difficult in the early stages of the disease. The aim of the study described here was to assess the correlation between transcranial sonography (TCS) and I-123-FP-CIT ([I-123]ioflupane, N-omega-fluoropropyl-2beta-carbomethoxy-3 beta-(4-[I-123]iodophenyl)nortropane) SPECT (single photon emission computed tomography) findings and the diagnosis of PD. A total of 49 patients were enrolled in the study: 29 patients with PD, 7 patients with other parkinsonian syndromes, 11 patients with essential tremor and 2 with psychogenic movement disorder. Substantia nigra echogenicity was measured using TCS. SPECT was performed using DaTSCAN ([I-123] ioflupane). TCS and SPECT findings were correlated in 84% of patients, with k = 0.62 (95% confidence interval: 0.38-0.86). TCS-measured substantia nigra echogenicity and SPECT-measured striatal binding ratio were negatively correlated (r = -0.326, p = 0.003). TCS/SPECT sensitivity, specificity and positive and

Název v anglickém jazyce

Transcranial sonography and I-123-FP-CIT single photon emission computed tomography in movement disorders

Popis výsledku anglicky

Diagnosis of Parkinson's disease (PD) can be difficult in the early stages of the disease. The aim of the study described here was to assess the correlation between transcranial sonography (TCS) and I-123-FP-CIT ([I-123]ioflupane, N-omega-fluoropropyl-2beta-carbomethoxy-3 beta-(4-[I-123]iodophenyl)nortropane) SPECT (single photon emission computed tomography) findings and the diagnosis of PD. A total of 49 patients were enrolled in the study: 29 patients with PD, 7 patients with other parkinsonian syndromes, 11 patients with essential tremor and 2 with psychogenic movement disorder. Substantia nigra echogenicity was measured using TCS. SPECT was performed using DaTSCAN ([I-123] ioflupane). TCS and SPECT findings were correlated in 84% of patients, with k = 0.62 (95% confidence interval: 0.38-0.86). TCS-measured substantia nigra echogenicity and SPECT-measured striatal binding ratio were negatively correlated (r = -0.326, p = 0.003). TCS/SPECT sensitivity, specificity and positive and

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Ultrasound in Medicine and Biology

ISSN

0301-5629

e-ISSN

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Svazek periodika

40

Číslo periodika v rámci svazku

10

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

7

Strana od-do

2365-2371

Kód UT WoS článku

000343144400006

EID výsledku v databázi Scopus

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