Changes of basal ganglia detected by transcrania sonography and 123I FP-CIT SPECT

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F10%3AA12011XC" target="_blank" >RIV/61988987:17110/10:A12011XC - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Changes of basal ganglia detected by transcrania sonography and 123I FP-CIT SPECT

Popis výsledku v původním jazyce

Diagnosis of Parkinson's disease (PD) could be difficult in early stages of the disease. Transcranial sonography (TCS) is able to detect structural changes in substantia nigra in PD patients. FP-CIT SPECT imaging could detect presynaptic dysfunction in several neurodegenerative disease. Methods: We examined 25 patients (19 male, mean age 57.2?8.4 years) during 2 years - 4 patients with ET, 12 PD patients, 7 PS patients, and 2 PMD patients. SN echogenicity and SN area were detected using TCS and SPECT evaluation of basal ganglia were performed using SPECT with DAT-ligand (123I-ioflupan) within 2 months after clinical examination. The sensitivity, specificity, positive predictive (PPV) and negative predictive (NPV) values for TCS and SPECT were evaluated.

Název v anglickém jazyce

Changes of basal ganglia detected by transcrania sonography and 123I FP-CIT SPECT

Popis výsledku anglicky

Diagnosis of Parkinson's disease (PD) could be difficult in early stages of the disease. Transcranial sonography (TCS) is able to detect structural changes in substantia nigra in PD patients. FP-CIT SPECT imaging could detect presynaptic dysfunction in several neurodegenerative disease. Methods: We examined 25 patients (19 male, mean age 57.2?8.4 years) during 2 years - 4 patients with ET, 12 PD patients, 7 PS patients, and 2 PMD patients. SN echogenicity and SN area were detected using TCS and SPECT evaluation of basal ganglia were performed using SPECT with DAT-ligand (123I-ioflupan) within 2 months after clinical examination. The sensitivity, specificity, positive predictive (PPV) and negative predictive (NPV) values for TCS and SPECT were evaluated.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

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Projekt

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Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

MOVEMENT DISORD

ISSN

0885-3185

e-ISSN

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Svazek periodika

2

Číslo periodika v rámci svazku

25

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

1

Strana od-do

575-575

Kód UT WoS článku

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EID výsledku v databázi Scopus

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