The relation between the sensitization to molecular components of inhalant allergens and food reactions in patients suffering from atopic dermatitis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F21%3A10421379" target="_blank" >RIV/00216208:11150/21:10421379 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00179906:_____/21:10421379

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=L3pg7m.z3f" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=L3pg7m.z3f</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/09540105.2020.1865281" target="_blank" >10.1080/09540105.2020.1865281</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The relation between the sensitization to molecular components of inhalant allergens and food reactions in patients suffering from atopic dermatitis

Popis výsledku v původním jazyce

To evaluate the relation between the sensitization to molecular components of inhalant allergens and the occurrence of food reactions in atopic dermatitis patients. Another aim is to evaluate the semi-quantification results of the ISAC Multiplex testing to reveal the relevance of the leading allergens. The complete dermatological and allergological examination including the examination of the sensitization to molecular components with Multiplex ISAC testing was performed. The food reactions to examined food allergens were confirmed in the open exposure test (history). Altogether 100 atopic dermatitis patients were examined - 48 men, 52 women, the average age 40.9 years. The leading molecular components are cysteine protease (Der f 1, Der p 1), NPC2 protease (Der f 2, Der p 2), Acidic glycoprotein (Alt a 1), PR 10 proteins (Bet v 1, Mal d 1, Aln g 1 and Cor 1.04), lipocalins (Can f 1, Fel d 4, Mus m 1, Equ c 1), uteroglobulin (Fel d 1), Kallikrein (Can f 5) and molecular components of Timothy and Bermuda grass (glycoprotein). The significantly higher occurrence of sensitization to molecular components Aln g 1, Bet v 1, Phl p 1, 2, 4, 5, 6, 11 was confirmed in patients suffering from reactions to peanuts, hazelnuts, celery, apple and peach.

Název v anglickém jazyce

The relation between the sensitization to molecular components of inhalant allergens and food reactions in patients suffering from atopic dermatitis

Popis výsledku anglicky

To evaluate the relation between the sensitization to molecular components of inhalant allergens and the occurrence of food reactions in atopic dermatitis patients. Another aim is to evaluate the semi-quantification results of the ISAC Multiplex testing to reveal the relevance of the leading allergens. The complete dermatological and allergological examination including the examination of the sensitization to molecular components with Multiplex ISAC testing was performed. The food reactions to examined food allergens were confirmed in the open exposure test (history). Altogether 100 atopic dermatitis patients were examined - 48 men, 52 women, the average age 40.9 years. The leading molecular components are cysteine protease (Der f 1, Der p 1), NPC2 protease (Der f 2, Der p 2), Acidic glycoprotein (Alt a 1), PR 10 proteins (Bet v 1, Mal d 1, Aln g 1 and Cor 1.04), lipocalins (Can f 1, Fel d 4, Mus m 1, Equ c 1), uteroglobulin (Fel d 1), Kallikrein (Can f 5) and molecular components of Timothy and Bermuda grass (glycoprotein). The significantly higher occurrence of sensitization to molecular components Aln g 1, Bet v 1, Phl p 1, 2, 4, 5, 6, 11 was confirmed in patients suffering from reactions to peanuts, hazelnuts, celery, apple and peach.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30102 - Immunology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Food and Agricultural Immunology

ISSN

0954-0105

e-ISSN

—

Svazek periodika

32

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

21

Strana od-do

33-53

Kód UT WoS článku

000606895000001

EID výsledku v databázi Scopus

2-s2.0-85100029039