Cluster analysis of allergen reagents in atopic dermatitis patients according to the specific IgE results in ALEX2 Allergy Explorer test
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F21%3A10432732" target="_blank" >RIV/00216208:11150/21:10432732 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00179906:_____/21:10432732
Výsledek na webu
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=waw4vefJDJ" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=waw4vefJDJ</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/09540105.2021.1978942" target="_blank" >10.1080/09540105.2021.1978942</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Cluster analysis of allergen reagents in atopic dermatitis patients according to the specific IgE results in ALEX2 Allergy Explorer test
Popis výsledku v původním jazyce
The aim of this study is the Cluster analysis of specific IgE results in ALEX2 Allergy Explorer test in atopic dermatitis (AD) patients. The complete dermatological and allergological examination including the examination of the sensitisation to allergen reagents with ALEX2 Allergy Explorer testing was performed. The cluster analysis (silhouette value) was processed for results of specific IgE and for clinical parameters. Altogether 100 atopic dermatitis patients were examined - 48 men, 52 women, the average age 40.9 years. Although the distribution of specific IgE results corresponds to the division into protein families, the links between specific IgE to allergens reagents in clusters are weak. Our results strongly point towards cross-reactivity for crustacean-allergic patients to desert locust, house cricket and stable flies. Combining the results of specific IgE for the basic allergen reagents together with the results of specific IgE for less common allergens can help in the estimating of allergic reactions.
Název v anglickém jazyce
Cluster analysis of allergen reagents in atopic dermatitis patients according to the specific IgE results in ALEX2 Allergy Explorer test
Popis výsledku anglicky
The aim of this study is the Cluster analysis of specific IgE results in ALEX2 Allergy Explorer test in atopic dermatitis (AD) patients. The complete dermatological and allergological examination including the examination of the sensitisation to allergen reagents with ALEX2 Allergy Explorer testing was performed. The cluster analysis (silhouette value) was processed for results of specific IgE and for clinical parameters. Altogether 100 atopic dermatitis patients were examined - 48 men, 52 women, the average age 40.9 years. Although the distribution of specific IgE results corresponds to the division into protein families, the links between specific IgE to allergens reagents in clusters are weak. Our results strongly point towards cross-reactivity for crustacean-allergic patients to desert locust, house cricket and stable flies. Combining the results of specific IgE for the basic allergen reagents together with the results of specific IgE for less common allergens can help in the estimating of allergic reactions.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
30216 - Dermatology and venereal diseases
Návaznosti výsledku
Projekt
—
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2021
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Food and Agricultural Immunology
ISSN
0954-0105
e-ISSN
—
Svazek periodika
32
Číslo periodika v rámci svazku
1
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
25
Strana od-do
625-649
Kód UT WoS článku
000702924600001
EID výsledku v databázi Scopus
2-s2.0-85122080457