Comparison of properties of tablets and energy profile of compaction of two spray-dried lactoses

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F13%3A10144248" target="_blank" >RIV/00216208:11160/13:10144248 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.ptfarm.pl/pub/File/Acta_Poloniae/2013/1/129-135.pdf" target="_blank" >http://www.ptfarm.pl/pub/File/Acta_Poloniae/2013/1/129-135.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Comparison of properties of tablets and energy profile of compaction of two spray-dried lactoses

Popis výsledku v původním jazyce

The paper compared two spray-dried lactoses Flowlac (R) 100 and SuperTab (R) 14SD from the standpoint of tensile strength and disintegration time of tablets, the effect of an addition of the lubricant magnesium stearate and silicified microcrystalline cellulose on these properties, and also from the standpoint of the energy profile of compression. The comparison of the values was performed at the compression force of 15 IN. The strength of tablets was higher in the case of SuperTab 14SD, an increase inthe concentration of magnesium stearate did not decrease tablet strength. Prosolv SMCC 90 increased the strength of tablets and made it equal for both lactoses, but it also increased the sensitivity to the added lubricant. The disintegration time of tablets was shorter in the case of SuperTab 14SD, an increased concentration of magnesium stearate prolonged it, and an addition of Prosolv SMCC 90 shortened it and made it equal for both lactoses. From the energy standpoint, the maximal ener

Název v anglickém jazyce

Comparison of properties of tablets and energy profile of compaction of two spray-dried lactoses

Popis výsledku anglicky

The paper compared two spray-dried lactoses Flowlac (R) 100 and SuperTab (R) 14SD from the standpoint of tensile strength and disintegration time of tablets, the effect of an addition of the lubricant magnesium stearate and silicified microcrystalline cellulose on these properties, and also from the standpoint of the energy profile of compression. The comparison of the values was performed at the compression force of 15 IN. The strength of tablets was higher in the case of SuperTab 14SD, an increase inthe concentration of magnesium stearate did not decrease tablet strength. Prosolv SMCC 90 increased the strength of tablets and made it equal for both lactoses, but it also increased the sensitivity to the added lubricant. The disintegration time of tablets was shorter in the case of SuperTab 14SD, an increased concentration of magnesium stearate prolonged it, and an addition of Prosolv SMCC 90 shortened it and made it equal for both lactoses. From the energy standpoint, the maximal ener

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FR - Farmakologie a lékárnická chemie

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta Poloniae Pharmaceutica

ISSN

0001-6837

e-ISSN

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Svazek periodika

70

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

7

Strana od-do

129-135

Kód UT WoS článku

000316432000015

EID výsledku v databázi Scopus

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