Antiplatelet Effects of Flavonoids Mediated by Inhibition of Arachidonic Acid Based Pathway

Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F16%3A10327781" target="_blank" >RIV/00216208:11160/16:10327781 - isvavai.cz</a>
Výsledek na webu
<a href="http://www.thieme-connect.de/DOI/DOI?10.1055/s-0035-1557902" target="_blank" >http://www.thieme-connect.de/DOI/DOI?10.1055/s-0035-1557902</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1055/s-0035-1557902" target="_blank" >10.1055/s-0035-1557902</a>

Jazyk výsledku
angličtina
Název v původním jazyce
Antiplatelet Effects of Flavonoids Mediated by Inhibition of Arachidonic Acid Based Pathway
Popis výsledku v původním jazyce
Flavonoids are important components of human diet and they have been claimed to possess a significant antiplatelet potential. 29 mainly natural flavonoids were tested for their antiplatelet effects on the arachidonic acid cascade. The isoflavonoids genistein and daidzein were shown to possess both marked cyclooxygenase-1 inhibitory activity and acted also as antagonists on thromboxane receptors. In conclusion, the consumption of few flavonoids in a diet, particularly of the isoflavonoids genistein and daidzein, may positively influence platelet aggregation.
Název v anglickém jazyce
Antiplatelet Effects of Flavonoids Mediated by Inhibition of Arachidonic Acid Based Pathway
Popis výsledku anglicky
Flavonoids are important components of human diet and they have been claimed to possess a significant antiplatelet potential. 29 mainly natural flavonoids were tested for their antiplatelet effects on the arachidonic acid cascade. The isoflavonoids genistein and daidzein were shown to possess both marked cyclooxygenase-1 inhibitory activity and acted also as antagonists on thromboxane receptors. In conclusion, the consumption of few flavonoids in a diet, particularly of the isoflavonoids genistein and daidzein, may positively influence platelet aggregation.

Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FR - Farmakologie a lékárnická chemie
OECD FORD obor
—

Projekt
<a href="/cs/project/GBP303%2F12%2FG163" target="_blank" >GBP303/12/G163: Centrum interakcí potravních doplňků s léčivy a nutrigenetiky</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění
2016
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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