Phylogeny, longevity and evolution of adaptive immunity

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F11%3A10100856" target="_blank" >RIV/00216208:11310/11:10100856 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68081766:_____/11:00367535

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Phylogeny, longevity and evolution of adaptive immunity

Popis výsledku v původním jazyce

Adaptive immunity is commonly viewed as a unique vertebrate feature. A misleading view on vertebrate longevity compared to non-vertebrate animals together with oversimplification of "invertebrate" phylogeny sometimes serves for justifying the limitationof adaptive immunity exclusively to vertebrates. However, here we emphasise that the borderline for differentiation between "innate" and "adaptive" immunity may be fuzzy and artificial. In invertebrates with a long lifespan some kind of acquired immunitycould exist. We therefore stress that the definition of "adaptivity" of immune response should reflect the system function instead of a certain molecular mechanism adopted. If these altered criteria are considered then several pieces of recent evidenceindicate that the adaptive immunity in animals might have arisen several times independently and in very different forms.

Název v anglickém jazyce

Phylogeny, longevity and evolution of adaptive immunity

Popis výsledku anglicky

Adaptive immunity is commonly viewed as a unique vertebrate feature. A misleading view on vertebrate longevity compared to non-vertebrate animals together with oversimplification of "invertebrate" phylogeny sometimes serves for justifying the limitationof adaptive immunity exclusively to vertebrates. However, here we emphasise that the borderline for differentiation between "innate" and "adaptive" immunity may be fuzzy and artificial. In invertebrates with a long lifespan some kind of acquired immunitycould exist. We therefore stress that the definition of "adaptivity" of immune response should reflect the system function instead of a certain molecular mechanism adopted. If these altered criteria are considered then several pieces of recent evidenceindicate that the adaptive immunity in animals might have arisen several times independently and in very different forms.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EG - Zoologie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Folia Zoologica

ISSN

0139-7893

e-ISSN

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Svazek periodika

60

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

6

Strana od-do

277-282

Kód UT WoS článku

000296301300011

EID výsledku v databázi Scopus

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