Separation efficiency of dual-selector systems in capillary electrophoresis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F14%3A10189962" target="_blank" >RIV/00216208:11310/14:10189962 - isvavai.cz</a>

Výsledek na webu

<a href="http://ac.els-cdn.com/S0021967314000296/1-s2.0-S0021967314000296-main.pdf?_tid=e994d2bc-a561-11e4-80e7-00000aab0f6b&acdnat=1422280247_11ddaa9da1d9edef54a04e4866c0c8da" target="_blank" >http://ac.els-cdn.com/S0021967314000296/1-s2.0-S0021967314000296-main.pdf?_tid=e994d2bc-a561-11e4-80e7-00000aab0f6b&acdnat=1422280247_11ddaa9da1d9edef54a04e4866c0c8da</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.chroma.2014.01.006" target="_blank" >10.1016/j.chroma.2014.01.006</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Separation efficiency of dual-selector systems in capillary electrophoresis

Popis výsledku v původním jazyce

We introduce an easy but highly descriptive model of separation efficiency of dual-selector systems in capillary electrophoresis.The model expresses effective mobilities of analytes in dual-selector mix-tures as a function of mixture composition and total concentration. The effective mobility follows the pattern familiar from single-selector systems, while complexation constant and mobility of the complex are replaced by the same but "overall" parameters and a total concentration of the mixture takes the role of a selector concentration. The overall parameters can be either calculated from the individual ones (an arbitrary mixture) or measured directly (a particular mixture). We inspected two model dual-selector systems consisting of heptakis(2,6-di-O-methyl)- -CD and -CD and of heptakis(2,6-di- O-methyl)- -CD and 6-O- -maltosyl- -CD, and ibuprofen and flurbiprofen as model analytes (pH 8.2, non-enantioselective separation).Adopting any optimization strategy typically used in single-se

Název v anglickém jazyce

Separation efficiency of dual-selector systems in capillary electrophoresis

Popis výsledku anglicky

We introduce an easy but highly descriptive model of separation efficiency of dual-selector systems in capillary electrophoresis.The model expresses effective mobilities of analytes in dual-selector mix-tures as a function of mixture composition and total concentration. The effective mobility follows the pattern familiar from single-selector systems, while complexation constant and mobility of the complex are replaced by the same but "overall" parameters and a total concentration of the mixture takes the role of a selector concentration. The overall parameters can be either calculated from the individual ones (an arbitrary mixture) or measured directly (a particular mixture). We inspected two model dual-selector systems consisting of heptakis(2,6-di-O-methyl)- -CD and -CD and of heptakis(2,6-di- O-methyl)- -CD and 6-O- -maltosyl- -CD, and ibuprofen and flurbiprofen as model analytes (pH 8.2, non-enantioselective separation).Adopting any optimization strategy typically used in single-se

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

<a href="/cs/project/GPP206%2F12%2FP630" target="_blank" >GPP206/12/P630: Sjednocený model (dynamické) chirální separace v kapilární zónové elektroforéze a integrované softwarové řešení</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Chromatography A

ISSN

0021-9673

e-ISSN

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Svazek periodika

1330

Číslo periodika v rámci svazku

February 2014

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

7

Strana od-do

82-88

Kód UT WoS článku

000331688400011

EID výsledku v databázi Scopus

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