Isopropyl derivative of cyclofructan 6 as chiral selector in liquid chromatography and capillary electrophoresis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F14%3A10210823" target="_blank" >RIV/00216208:11310/14:10210823 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989592:15310/14:33151624

Výsledek na webu

<a href="http://ac.els-cdn.com/S0021967314003082/1-s2.0-S0021967314003082-main.pdf?_tid=4b7d2aa8-a565-11e4-9f63-00000aab0f27&acdnat=1422281700_ba51d203583eb9c739089a75bba077dd" target="_blank" >http://ac.els-cdn.com/S0021967314003082/1-s2.0-S0021967314003082-main.pdf?_tid=4b7d2aa8-a565-11e4-9f63-00000aab0f27&acdnat=1422281700_ba51d203583eb9c739089a75bba077dd</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.chroma.2014.02.061" target="_blank" >10.1016/j.chroma.2014.02.061</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Isopropyl derivative of cyclofructan 6 as chiral selector in liquid chromatography and capillary electrophoresis

Popis výsledku v původním jazyce

Cyclofructans and preferentially their derivatives can serve as chiral selectors for the separation of different enantiomers/atropisomers. Moreover, the strong ionophoric nature of the 18-crown-6 ether core of cyclofructan 6 for barium cations may be exploited to enhance or modify enantioselectivity. In this work isopropyl-cyclofructan-6 was used as a chiral selector for the separation of binaphthyl atropisomers in HPLC and CE. The data from both separation systems were compared with each other. While in HPLC the chiral selector was bonded to silica gel to afford a chiral stationary phase, in capillary electrophoresis it was reely mobile n the background electrolytes (BGE). This significant difference is reflected in the separation potential of the twoseparation systems. All five analytes could be baseline separated in HPLC (reversed phase mode) while only one derivative was baseline resolved in CE. This result was attributed to the more rigid nature of the immobilized chiral selector

Název v anglickém jazyce

Isopropyl derivative of cyclofructan 6 as chiral selector in liquid chromatography and capillary electrophoresis

Popis výsledku anglicky

Cyclofructans and preferentially their derivatives can serve as chiral selectors for the separation of different enantiomers/atropisomers. Moreover, the strong ionophoric nature of the 18-crown-6 ether core of cyclofructan 6 for barium cations may be exploited to enhance or modify enantioselectivity. In this work isopropyl-cyclofructan-6 was used as a chiral selector for the separation of binaphthyl atropisomers in HPLC and CE. The data from both separation systems were compared with each other. While in HPLC the chiral selector was bonded to silica gel to afford a chiral stationary phase, in capillary electrophoresis it was reely mobile n the background electrolytes (BGE). This significant difference is reflected in the separation potential of the twoseparation systems. All five analytes could be baseline separated in HPLC (reversed phase mode) while only one derivative was baseline resolved in CE. This result was attributed to the more rigid nature of the immobilized chiral selector

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

—

Projekt

<a href="/cs/project/LH11018" target="_blank" >LH11018: Cyklofruktany a jejich deriváty jako nové chirální selektory pro kapalinovou chromatografii a kapilární elektroforézu</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Chromatography A

ISSN

0021-9673

e-ISSN

—

Svazek periodika

1338

Číslo periodika v rámci svazku

APRIL 18

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

4

Strana od-do

197-200

Kód UT WoS článku

000334137200023

EID výsledku v databázi Scopus

—