APOFERRITIN: PROTEIN NANOCARRIER FOR TARGETED DELIVERY

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10297997" target="_blank" >RIV/00216208:11310/15:10297997 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11130/15:10297997 RIV/00064203:_____/15:10297997

Výsledek na webu

<a href="http://iapc-obp.com/assets/files/883189NBDD.pdf" target="_blank" >http://iapc-obp.com/assets/files/883189NBDD.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

APOFERRITIN: PROTEIN NANOCARRIER FOR TARGETED DELIVERY

Popis výsledku v původním jazyce

The apoferritin protein nanocage is a very suitable molecule for use as a drug delivery vehicle. Its properties, such as size, excellent biocompatibility, easy modification and simple encapsulation protocol based on structural changes in different pH, present a large advantage when compared to the other nanocarriers. It contains multiple channels in its structure, employable for small nanoparticle synthesis. Due to the encapsulation procedure, a wide variety of different molecules can be encapsulated within its cavity. It can therefore be used for simple chemotherapy, but also the combination of therapy with diagnostics, chemotherapy and photodynamic therapy, gene therapy or hyperthermia therapy. It can be used in not only the treatment of cancer but also other diseases, including bacterial infections. The size of apoferritin is suitable for passive targeting to tumours and its surface can be modified with a variety of targeting moieties for specific use. Due to all these advantages, a

Název v anglickém jazyce

APOFERRITIN: PROTEIN NANOCARRIER FOR TARGETED DELIVERY

Popis výsledku anglicky

The apoferritin protein nanocage is a very suitable molecule for use as a drug delivery vehicle. Its properties, such as size, excellent biocompatibility, easy modification and simple encapsulation protocol based on structural changes in different pH, present a large advantage when compared to the other nanocarriers. It contains multiple channels in its structure, employable for small nanoparticle synthesis. Due to the encapsulation procedure, a wide variety of different molecules can be encapsulated within its cavity. It can therefore be used for simple chemotherapy, but also the combination of therapy with diagnostics, chemotherapy and photodynamic therapy, gene therapy or hyperthermia therapy. It can be used in not only the treatment of cancer but also other diseases, including bacterial infections. The size of apoferritin is suitable for passive targeting to tumours and its surface can be modified with a variety of targeting moieties for specific use. Due to all these advantages, a

Druh

C - Kapitola v odborné knize

CEP obor

CE - Biochemie

OECD FORD obor

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Projekt

<a href="/cs/project/GA14-18344S" target="_blank" >GA14-18344S: Vývoj nanočástic obsahujících cytostatika a enzymy pro zlepšení chemotherapie lidských neuroblastomů a studium mechanismu jejich působení</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Nano Based Drug Delliivery

ISBN

978-953-56942-2-9

Počet stran výsledku

22

Strana od-do

217-238

Počet stran knihy

604

Název nakladatele

IAPC Publishing

Místo vydání

Záhřeb

Kód UT WoS kapitoly

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