Voltammetric Detection of Catecholamine Metabolites Using Troger's Base Modified Electrode

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F18%3A10375872" target="_blank" >RIV/00216208:11310/18:10375872 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60461373:22340/18:43915430 RIV/60461373:22810/18:43915430 RIV/00216208:11110/18:10375872

Výsledek na webu

<a href="https://doi.org/10.1002/elan.201700635" target="_blank" >https://doi.org/10.1002/elan.201700635</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/elan.201700635" target="_blank" >10.1002/elan.201700635</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Voltammetric Detection of Catecholamine Metabolites Using Troger's Base Modified Electrode

Popis výsledku v původním jazyce

The advantage of surface modification of voltammetric sensor for determination of catecholamine metabolites such as vanillyl mandelic acid (VMA) and homovanillic acid (HVA) is discussed. The amino-substituted coumarin derivative of Troger&apos;s base was deposi-ted on a graphite screen-printed electrode (poly(CTB)/G/SPE) cycling the electrode potential between 0 and 1.2V in 5 mL CH2Cl2 containing 1x10(-3)molL(-1) tetrabutylammonium tetrafluoroborate and 20L 0.1molL(-1) HCl. The poly(CTB) functions as both a selective recognition and pre-concentrator agent for catecholamine metabolites. The high sensitivity of the voltammetric sensor coated by a poly(CTB) film toward VMA was achieved despite the high structural similarity between the two tested metabolites. We presume the voltammetric detection of these species is based on selective binding by a poly(CTB) film supported by its good adherence to the electrode substrate. The voltammetric signals of VMA were observable in the concentration range 10-100molL(-1) (LOD=0.2molL(-1)) and 20-60molL(-1) (LOD=10molL(-1)) in the model and synthethic urine samples, respectively.

Název v anglickém jazyce

Voltammetric Detection of Catecholamine Metabolites Using Troger's Base Modified Electrode

Popis výsledku anglicky

The advantage of surface modification of voltammetric sensor for determination of catecholamine metabolites such as vanillyl mandelic acid (VMA) and homovanillic acid (HVA) is discussed. The amino-substituted coumarin derivative of Troger&apos;s base was deposi-ted on a graphite screen-printed electrode (poly(CTB)/G/SPE) cycling the electrode potential between 0 and 1.2V in 5 mL CH2Cl2 containing 1x10(-3)molL(-1) tetrabutylammonium tetrafluoroborate and 20L 0.1molL(-1) HCl. The poly(CTB) functions as both a selective recognition and pre-concentrator agent for catecholamine metabolites. The high sensitivity of the voltammetric sensor coated by a poly(CTB) film toward VMA was achieved despite the high structural similarity between the two tested metabolites. We presume the voltammetric detection of these species is based on selective binding by a poly(CTB) film supported by its good adherence to the electrode substrate. The voltammetric signals of VMA were observable in the concentration range 10-100molL(-1) (LOD=0.2molL(-1)) and 20-60molL(-1) (LOD=10molL(-1)) in the model and synthethic urine samples, respectively.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Electroanalysis

ISSN

1040-0397

e-ISSN

—

Svazek periodika

30

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

6

Strana od-do

734-739

Kód UT WoS článku

000429708900021

EID výsledku v databázi Scopus

2-s2.0-85040587352