A virtual reality task based on animal research - spatial learning and memory in patients after the first episode of schizophrenia

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F14%3A10284163" target="_blank" >RIV/00216208:11320/14:10284163 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/67985823:_____/14:00428984 RIV/00216208:11120/14:43908569 RIV/00023752:_____/14:43914583

Výsledek na webu

<a href="http://dx.doi.org/10.3389/fnbeh.2014.00157" target="_blank" >http://dx.doi.org/10.3389/fnbeh.2014.00157</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3389/fnbeh.2014.00157" target="_blank" >10.3389/fnbeh.2014.00157</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A virtual reality task based on animal research - spatial learning and memory in patients after the first episode of schizophrenia

Popis výsledku v původním jazyce

Objectives: Cognitive deficit is considered to be a characteristic feature of schizophrenia disorder. A similar cognitive dysfunction was demonstrated in animal models of schizophrenia. However, the poor comparability of methods used to assess cognitionin animals and humans could be responsible for low predictive validity of current animal models. In order to assess spatial abilities in schizophrenia and compare our results with the data obtained in animal models, we designed a virtual analog of the Morris water maze (MWM), the virtual Four Goals Navigation (vFGN) task. Methods: Twenty-nine patients after the first psychotic episode with schizophrenia symptoms and a matched group of healthy volunteers performed the vFGN task. They were required to find and remember four hidden goal positions in an enclosed virtual arena. The task consisted of two parts. The Reference memory (RM) session with a stable goal position was designed to test spatial learning. The Delayed-matching-to-place (D

Název v anglickém jazyce

A virtual reality task based on animal research - spatial learning and memory in patients after the first episode of schizophrenia

Popis výsledku anglicky

Objectives: Cognitive deficit is considered to be a characteristic feature of schizophrenia disorder. A similar cognitive dysfunction was demonstrated in animal models of schizophrenia. However, the poor comparability of methods used to assess cognitionin animals and humans could be responsible for low predictive validity of current animal models. In order to assess spatial abilities in schizophrenia and compare our results with the data obtained in animal models, we designed a virtual analog of the Morris water maze (MWM), the virtual Four Goals Navigation (vFGN) task. Methods: Twenty-nine patients after the first psychotic episode with schizophrenia symptoms and a matched group of healthy volunteers performed the vFGN task. They were required to find and remember four hidden goal positions in an enclosed virtual arena. The task consisted of two parts. The Reference memory (RM) session with a stable goal position was designed to test spatial learning. The Delayed-matching-to-place (D

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Frontiers in Behavioral Neuroscience

ISSN

1662-5153

e-ISSN

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Svazek periodika

8

Číslo periodika v rámci svazku

Neuveden

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

15

Strana od-do

1-15

Kód UT WoS článku

000336793300001

EID výsledku v databázi Scopus

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