One-pot synthesis of maghemite nanocrystals across aqueous and organic solvents for magnetic hyperthermia

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F18%3A10379312" target="_blank" >RIV/00216208:11320/18:10379312 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1016/j.apmt.2018.06.003" target="_blank" >https://doi.org/10.1016/j.apmt.2018.06.003</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.apmt.2018.06.003" target="_blank" >10.1016/j.apmt.2018.06.003</a>

Jazyk výsledku

angličtina

Název v původním jazyce

One-pot synthesis of maghemite nanocrystals across aqueous and organic solvents for magnetic hyperthermia

Popis výsledku v původním jazyce

Superparamagnetic iron oxide nanocrystals (SPIONs) continue to receive intensive interest due to their significant prospects in biomedical applications. However, a critical requirement for such applications is the ability to synthesise high quality nanocrystals that are not only readily dispersible in aqueous solvents, but also retain good magnetic properties in an aqueous medium. This is not easy to achieve because, although organic solvent-based syntheses provide better control over SPIONs properties, their magnetic properties in particular, tend to deteriorate during aqueous phase transfer. In the current work, we propose a new route for the synthesis of high quality SPIONs using triethylamine (TEA) as a dynamic amphiphilic molecule. We demonstrate that in a single step, TEA can directly synthesise SPIONs that are readily dispersible in both aqueous and organic media. We further demonstrate the versatility of TEA in facilitating one-step phase transfer of SPIONs from organic to aqueous solvents. We then extend the applicability of this approach to demonstrate for the first time that organic molecules-capped SPIONs can also be directly dispersed in aqueous solvents. These SPIONs show remarkable potential for hyperthermia, as demonstrated through their outstanding magnetic field induced heating performance, which improves after their phase transfer to the aqueous phase. The current study establishes the importance of a suitable nanoparticle phase transfer protocol to ensure that the final product retains all the desirable application-focussed properties. (C) 2018 Published by Elsevier Ltd.

Název v anglickém jazyce

One-pot synthesis of maghemite nanocrystals across aqueous and organic solvents for magnetic hyperthermia

Popis výsledku anglicky

Superparamagnetic iron oxide nanocrystals (SPIONs) continue to receive intensive interest due to their significant prospects in biomedical applications. However, a critical requirement for such applications is the ability to synthesise high quality nanocrystals that are not only readily dispersible in aqueous solvents, but also retain good magnetic properties in an aqueous medium. This is not easy to achieve because, although organic solvent-based syntheses provide better control over SPIONs properties, their magnetic properties in particular, tend to deteriorate during aqueous phase transfer. In the current work, we propose a new route for the synthesis of high quality SPIONs using triethylamine (TEA) as a dynamic amphiphilic molecule. We demonstrate that in a single step, TEA can directly synthesise SPIONs that are readily dispersible in both aqueous and organic media. We further demonstrate the versatility of TEA in facilitating one-step phase transfer of SPIONs from organic to aqueous solvents. We then extend the applicability of this approach to demonstrate for the first time that organic molecules-capped SPIONs can also be directly dispersed in aqueous solvents. These SPIONs show remarkable potential for hyperthermia, as demonstrated through their outstanding magnetic field induced heating performance, which improves after their phase transfer to the aqueous phase. The current study establishes the importance of a suitable nanoparticle phase transfer protocol to ensure that the final product retains all the desirable application-focussed properties. (C) 2018 Published by Elsevier Ltd.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10302 - Condensed matter physics (including formerly solid state physics, supercond.)

Projekt

<a href="/cs/project/LM2011025" target="_blank" >LM2011025: LMNT - Laboratoře magnetizmu a nízkých teplot - provoz a rozvoj národní výzkumné infrastruktury</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Applied Materials Today

ISSN

2352-9407

e-ISSN

—

Svazek periodika

12

Číslo periodika v rámci svazku

září

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

10

Strana od-do

250-259

Kód UT WoS článku

000443213700022

EID výsledku v databázi Scopus

2-s2.0-85048725388