Antiradical phenolic compounds from Cynara cardunculus

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F00%3A00003561" target="_blank" >RIV/00216224:14110/00:00003561 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Antiradical phenolic compounds from Cynara cardunculus

Popis výsledku v původním jazyce

Extracts from artichoke (Cynara scolymus L.) or cardoon (Cynara cardunculus L., Asteraceae), are widely used in phytotherapy as choleretic, hypocholesterolemic and hepatoprotective agents (Kraft, 1997). The cholesterol-lowering effect of artichoke extracts was confirmed by numerous animal experiments and recently by a controlled clinical trial. The possible mechanism of hypocholesterolemic activity involves choleretic action, reduction of cholesterol biosynthesis and inhibition of low density lipoprotein oxidation (Pittler and Ernst, 1998). The antiatherosclerotic and antihepatotoxic activities can be mediated by antioxidative action of the artichoke extract. These activities have been ascribed to the phenolic compounds present in the extract. According to HPLC analysis, the methanol extract of C. cardunculus leaves contained three main phenolic components, 5-caffeoylquinic acid (chlorogenic acid), 1,5-dicaffeoylquinic acid (1,5-DiCQA) and flavonoid luteolin-7-O-glucoside. However, caf

Název v anglickém jazyce

Antiradical phenolic compounds from Cynara cardunculus

Popis výsledku anglicky

Extracts from artichoke (Cynara scolymus L.) or cardoon (Cynara cardunculus L., Asteraceae), are widely used in phytotherapy as choleretic, hypocholesterolemic and hepatoprotective agents (Kraft, 1997). The cholesterol-lowering effect of artichoke extracts was confirmed by numerous animal experiments and recently by a controlled clinical trial. The possible mechanism of hypocholesterolemic activity involves choleretic action, reduction of cholesterol biosynthesis and inhibition of low density lipoprotein oxidation (Pittler and Ernst, 1998). The antiatherosclerotic and antihepatotoxic activities can be mediated by antioxidative action of the artichoke extract. These activities have been ascribed to the phenolic compounds present in the extract. According to HPLC analysis, the methanol extract of C. cardunculus leaves contained three main phenolic components, 5-caffeoylquinic acid (chlorogenic acid), 1,5-dicaffeoylquinic acid (1,5-DiCQA) and flavonoid luteolin-7-O-glucoside. However, caf

Druh

D - Stať ve sborníku

CEP obor

CE - Biochemie

OECD FORD obor

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Projekt

<a href="/cs/project/GA303%2F00%2FD062" target="_blank" >GA303/00/D062: Biologická dostupnost a mechanismus antioxidačního účinku fenolických kyselin a lignanů</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2000

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

In Polyphenols Communication 2000. XX th International Conference on Polyphenols

ISBN

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ISSN

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e-ISSN

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Počet stran výsledku

2

Strana od-do

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Název nakladatele

S.Martens, D.Treutter, G.Forkmann, str.425

Místo vydání

Freising-Weihenstephan, BRD

Místo konání akce

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Datum konání akce

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Typ akce podle státní příslušnosti

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Kód UT WoS článku

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