Interakce kanabinoidu metanandamidu s procesy sensitizace k behaviorálním a imunologickým účinklům metamfetaminu u myší

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F04%3A00010248" target="_blank" >RIV/00216224:14110/04:00010248 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Interaction of cannabinoid methanandamide with processes of sensitization to both behavioral and immunological methamphetamine effects in mice.

Popis výsledku v původním jazyce

The phenomenon of sensitization enhancing usually stimulant behavioral response to repeatedly administered drugs of abuse has been described both in laboratory animals and human beings. There is also data available confirming a cross-sensitization between different types of drugs of abuse supporting further the hypothesis that repeated use of one drug of abuse may facilitate the consumption of other drugs. Previously we confirmed the sensitization to methamphetamine (MET) stimulatory effect on locomotor/exploratory behavior, and also to its inhibitory influence on aggression in mice. Furthermore, such sensitization was present in mice cross-sensitized with cannabinoid methanandamide (CAN). Our experiences with behavioral as well as immunological profiles of different cannabinoids received in our collaborative studies with Israel colleagues (Mechoulam R., Fride E.) gave rise to the present study comparing cross-sensitization with CAN to behavioral MET effects with their influences on im

Název v anglickém jazyce

Interaction of cannabinoid methanandamide with processes of sensitization to both behavioral and immunological methamphetamine effects in mice.

Popis výsledku anglicky

The phenomenon of sensitization enhancing usually stimulant behavioral response to repeatedly administered drugs of abuse has been described both in laboratory animals and human beings. There is also data available confirming a cross-sensitization between different types of drugs of abuse supporting further the hypothesis that repeated use of one drug of abuse may facilitate the consumption of other drugs. Previously we confirmed the sensitization to methamphetamine (MET) stimulatory effect on locomotor/exploratory behavior, and also to its inhibitory influence on aggression in mice. Furthermore, such sensitization was present in mice cross-sensitized with cannabinoid methanandamide (CAN). Our experiences with behavioral as well as immunological profiles of different cannabinoids received in our collaborative studies with Israel colleagues (Mechoulam R., Fride E.) gave rise to the present study comparing cross-sensitization with CAN to behavioral MET effects with their influences on im

Druh

D - Stať ve sborníku

CEP obor

FR - Farmakologie a lékárnická chemie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2004

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Abstracts - NIDA International Forum 2004, San Juan, Puerto Rico

ISBN

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ISSN

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e-ISSN

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Počet stran výsledku

1

Strana od-do

90

Název nakladatele

US National Institute on Drug Abuse

Místo vydání

USA

Místo konání akce

San Juan, Puerto Rico

Datum konání akce

1. 1. 2004

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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