Development of baroreflex control of heart rate in children and adolescents

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F05%3A00013676" target="_blank" >RIV/00216224:14110/05:00013676 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Development of baroreflex control of heart rate in children and adolescents

Popis výsledku v původním jazyce

The aim of the study was to investigate the development of noninvasively determined BRS in children and young adults. 467 healthy subjects (11 - 21 years) were examined and divided into 11 age-subgroups according to the age. Beat-to-beat values of interbeat intervals (IBI), systolic (SBP) and diastolic (DBP) blood pressure were measured, and their power spectra were calculated. BRS was age-independent in this group. There were estimated limits of BRS for the whole group: 5th percentile - 3.9 ms/mmHg; 50th - 9.0; 95th - 19.4. Significant relationship was found between BRS and mean IBI (r = 0.44) with increase of IBI 20 ms/year (11-17 years), and 8 ms/year (18-21 y). BRSf decreased significantly with age (r = -0.35), the average decrease was 0.9 mHz/mmHg per year. The age-dependent decline of BRSf (mHz/mmHg) is present, but BRS (ms/mmHg) did not change with age in children and young adults.

Název v anglickém jazyce

Development of baroreflex control of heart rate in children and adolescents

Popis výsledku anglicky

The aim of the study was to investigate the development of noninvasively determined BRS in children and young adults. 467 healthy subjects (11 - 21 years) were examined and divided into 11 age-subgroups according to the age. Beat-to-beat values of interbeat intervals (IBI), systolic (SBP) and diastolic (DBP) blood pressure were measured, and their power spectra were calculated. BRS was age-independent in this group. There were estimated limits of BRS for the whole group: 5th percentile - 3.9 ms/mmHg; 50th - 9.0; 95th - 19.4. Significant relationship was found between BRS and mean IBI (r = 0.44) with increase of IBI 20 ms/year (11-17 years), and 8 ms/year (18-21 y). BRSf decreased significantly with age (r = -0.35), the average decrease was 0.9 mHz/mmHg per year. The age-dependent decline of BRSf (mHz/mmHg) is present, but BRS (ms/mmHg) did not change with age in children and young adults.

Druh

O - Ostatní výsledky

CEP obor

ED - Fyziologie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2005

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů