Korelace mezi abnormálním termickým prahem a hustotou intraepidermáních nervových vláken u neuropatie tenkých vláken

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F05%3A00014760" target="_blank" >RIV/00216224:14110/05:00014760 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Correlation between abnormal thermal threshold and intra-epidermal nerve fibre density in small fibre neuropathy

Popis výsledku v původním jazyce

Clinical diagnosis of small fibre neuropathy (SFN) is based on positive sensory symptoms (burning feet). Thermal threshold testing (TTT) and Intra-epidermal nerve fibre densities (IENFD) using skin biopsy are methods used for verification of somatic small fibre involvement. Aim of the study was to evaluate the correlation between electrophysiological tests and skin biopsy findings in patients with small fiber involvement. PGP 9.5-immunoreactive intra-epidermal nerve fibre density was evaluated in skin biopsy samples from the distal calf in a two subgroups of patients with clinical signs of SFN and abnormal TTT findings: pure SFN group without clinical and EMG signs of thick fibre involvement (38 cases) and mixed neuropathy group (29 cases). TTT comprised both reaction time inclusive ane exclusive methods from both upper and lower extremities. Autonomic tests (Sympathetic skin response and cardiovascular tests based of heart rate variability) were also performed in all cases. Abnormal I

Název v anglickém jazyce

Correlation between abnormal thermal threshold and intra-epidermal nerve fibre density in small fibre neuropathy

Popis výsledku anglicky

Clinical diagnosis of small fibre neuropathy (SFN) is based on positive sensory symptoms (burning feet). Thermal threshold testing (TTT) and Intra-epidermal nerve fibre densities (IENFD) using skin biopsy are methods used for verification of somatic small fibre involvement. Aim of the study was to evaluate the correlation between electrophysiological tests and skin biopsy findings in patients with small fiber involvement. PGP 9.5-immunoreactive intra-epidermal nerve fibre density was evaluated in skin biopsy samples from the distal calf in a two subgroups of patients with clinical signs of SFN and abnormal TTT findings: pure SFN group without clinical and EMG signs of thick fibre involvement (38 cases) and mixed neuropathy group (29 cases). TTT comprised both reaction time inclusive ane exclusive methods from both upper and lower extremities. Autonomic tests (Sympathetic skin response and cardiovascular tests based of heart rate variability) were also performed in all cases. Abnormal I

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2005

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European Journal of Neurology

ISSN

1351-5101

e-ISSN

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Svazek periodika

12

Číslo periodika v rámci svazku

Suppl. 2

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

1

Strana od-do

219

Kód UT WoS článku

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EID výsledku v databázi Scopus

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