Occurrence of quaternary benzo[c]phenanthridine alkaloids in Stylophorum lasiocarpum (Oliv.) fedde

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F12%3A00060640" target="_blank" >RIV/00216224:14110/12:00060640 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Occurrence of quaternary benzo[c]phenanthridine alkaloids in Stylophorum lasiocarpum (Oliv.) fedde

Popis výsledku v původním jazyce

For a long time, quaternary benzo[c]phenanthridine alkaloids (QBAs) are known to exhibit diverse biological effects. A great deal of attention is devoted to the main alkaloids sanguinarine (SA ) and chelerythrine (CHE) and their cytotoxicity and induction of apoptosis. These alkaloids also display important anti-proliferative activities against cancer cell lines and have been discussed as potential cytostatic drugs for cancer treatment. In the last years also the other QBAs have received increased attention and new information regarding their biological activities has been published.

Název v anglickém jazyce

Occurrence of quaternary benzo[c]phenanthridine alkaloids in Stylophorum lasiocarpum (Oliv.) fedde

Popis výsledku anglicky

For a long time, quaternary benzo[c]phenanthridine alkaloids (QBAs) are known to exhibit diverse biological effects. A great deal of attention is devoted to the main alkaloids sanguinarine (SA ) and chelerythrine (CHE) and their cytotoxicity and induction of apoptosis. These alkaloids also display important anti-proliferative activities against cancer cell lines and have been discussed as potential cytostatic drugs for cancer treatment. In the last years also the other QBAs have received increased attention and new information regarding their biological activities has been published.

Druh

O - Ostatní výsledky

CEP obor

CE - Biochemie

OECD FORD obor

—

Projekt

<a href="/cs/project/LH12176" target="_blank" >LH12176: Benzofenanthridinové alkaloidy - studium účinků na celulární a molekulární úrovni</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů