Spectral Peak Frequency in Low-Frequency Band in Cross Spectra of Blood Pressure and Heart Rate Fluctuations in Young Type 1 Diabetic Patients
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F12%3A00061311" target="_blank" >RIV/00216224:14110/12:00061311 - isvavai.cz</a>
Výsledek na webu
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DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Spectral Peak Frequency in Low-Frequency Band in Cross Spectra of Blood Pressure and Heart Rate Fluctuations in Young Type 1 Diabetic Patients
Popis výsledku v původním jazyce
In this study we tested whether joint evaluation of the frequency (fcs) at which maxima of power in the cross-spectra between the variability in systolic blood pressure and inter-beat intervals in the range of 0.06-0.12 Hz occur together with the quantification of baroreflex sensitivity (BRS) may improve early detection of autonomic dysfunction in type 1 diabetes mellitus (T1DM). We measured 14 T1DM patients (age 20.3-24.2 years, DM duration 10.4-14.2 years, without any signs of autonomic neuropathy) and 14 age-matched controls (Co). Finger arterial blood pressure was continuously recorded by Finapres for one hour. BRS and fcs were determined by the spectral method. Receiver-operating curves (ROC) were calculated for fcs, BRS, and a combination of bothfactors determined as F(z)=1/(1+exp(-z)), z=3.09?0.013*BRS? 0.027*fcs. T1DM had significantly lower fcs than Co (T1DM: 88.8plusminus 6.7 vs. Co: 93.7plusminus 3.8 mHz; p<0.05), and a tendency towards lower BRS compared to Co (T1DM: 10
Název v anglickém jazyce
Spectral Peak Frequency in Low-Frequency Band in Cross Spectra of Blood Pressure and Heart Rate Fluctuations in Young Type 1 Diabetic Patients
Popis výsledku anglicky
In this study we tested whether joint evaluation of the frequency (fcs) at which maxima of power in the cross-spectra between the variability in systolic blood pressure and inter-beat intervals in the range of 0.06-0.12 Hz occur together with the quantification of baroreflex sensitivity (BRS) may improve early detection of autonomic dysfunction in type 1 diabetes mellitus (T1DM). We measured 14 T1DM patients (age 20.3-24.2 years, DM duration 10.4-14.2 years, without any signs of autonomic neuropathy) and 14 age-matched controls (Co). Finger arterial blood pressure was continuously recorded by Finapres for one hour. BRS and fcs were determined by the spectral method. Receiver-operating curves (ROC) were calculated for fcs, BRS, and a combination of bothfactors determined as F(z)=1/(1+exp(-z)), z=3.09?0.013*BRS? 0.027*fcs. T1DM had significantly lower fcs than Co (T1DM: 88.8plusminus 6.7 vs. Co: 93.7plusminus 3.8 mHz; p<0.05), and a tendency towards lower BRS compared to Co (T1DM: 10
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FB - Endokrinologie, diabetologie, metabolismus, výživa
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
Z - Vyzkumny zamer (s odkazem do CEZ)
Ostatní
Rok uplatnění
2012
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Physiological Research
ISSN
0862-8408
e-ISSN
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Svazek periodika
61
Číslo periodika v rámci svazku
4
Stát vydavatele periodika
CZ - Česká republika
Počet stran výsledku
8
Strana od-do
347-354
Kód UT WoS článku
000309194600002
EID výsledku v databázi Scopus
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