Senzor pro sledování interakcí mezi biologicky významnými těžkými kovy a glutathioneinem

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F07%3A00020268" target="_blank" >RIV/00216224:14310/07:00020268 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62156489:43210/07:00107862 RIV/62157124:16270/07:00001309

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

A sensor for investigating the interaction between biologically important heavy metals and glutathione

Popis výsledku v původním jazyce

Glutathione (GSH) is the water-soluble tripeptide playing a crucial role in number of cellular reactions including detoxification of heavy metals. Glutathione can be found both in oxidized (GSSG) and reduced (GSH) state. The aim of this work was to utilize the electrochemical methods for determining of glutathiones and for investigating interaction of GSH and cadmium, zinc, copper and nickel ions or food supplement for animal nutrition. It clearly follows from the results obtained that GSH and GSSG canbe distinguished by cyclic voltammetry whereas the height of their current response is proportional to their concentration. Moreover, we were concerned with studying of these interactions by cyclic voltammetry. The markedly changes of GSH signal were observed and discussed. The highest decrease of GSH reductive signal cause cadmium ions followed by zinc, nickel and copper ones. Moreover we observed that reductive GSH signal gradually decreased (about 9 %) with increasing concentration of

Název v anglickém jazyce

A sensor for investigating the interaction between biologically important heavy metals and glutathione

Popis výsledku anglicky

Glutathione (GSH) is the water-soluble tripeptide playing a crucial role in number of cellular reactions including detoxification of heavy metals. Glutathione can be found both in oxidized (GSSG) and reduced (GSH) state. The aim of this work was to utilize the electrochemical methods for determining of glutathiones and for investigating interaction of GSH and cadmium, zinc, copper and nickel ions or food supplement for animal nutrition. It clearly follows from the results obtained that GSH and GSSG canbe distinguished by cyclic voltammetry whereas the height of their current response is proportional to their concentration. Moreover, we were concerned with studying of these interactions by cyclic voltammetry. The markedly changes of GSH signal were observed and discussed. The highest decrease of GSH reductive signal cause cadmium ions followed by zinc, nickel and copper ones. Moreover we observed that reductive GSH signal gradually decreased (about 9 %) with increasing concentration of

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CG - Elektrochemie

OECD FORD obor

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Projekt

<a href="/cs/project/GP525%2F04%2FP132" target="_blank" >GP525/04/P132: Studium obranných mechanismů rostlin při stresu způsobeném těžkými kovy</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2007

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Czech J. Anim. Sci.

ISSN

1212-1819

e-ISSN

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Svazek periodika

52

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

6

Strana od-do

37-43

Kód UT WoS článku

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EID výsledku v databázi Scopus

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