The nematobacterial complex Heterorhabditis Photorhabdus as infection model for Drosophila immunity

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F09%3A00048345" target="_blank" >RIV/00216224:14310/09:00048345 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The nematobacterial complex Heterorhabditis Photorhabdus as infection model for Drosophila immunity

Popis výsledku v původním jazyce

Entomopathogenic nematodes (EPNs) of the genera Heterorhabditis and Steinernema are obligate and lethal insect parasites, in recent years they have been used increasingly as biological control agents for pest insects. Animals from the third developmentalstage of nematodes are called dauer juvenile (DJ) or infective juveniles (IJ). IJs occur free living in the soil and are capable of seeking out hosts and penetrate them through either the cuticle or natural orifices. EPNs are symbiotically associated with bacteria of either of the genera Photorhabdus and Xenorhabdus. The bacterial symbionts are essential to kill the insect host (usually within 24-48 hours) and to digest host tissues. Drosophila larvae are more resistant to nematode infection than Galleria mellonella where all larvae can be killed with low nematode dose. The tripartite model (Drosophila, nematodes, bacteria) was recently established by Hallem el al. (2007); we used their modified method to optimize conditions for infect

Název v anglickém jazyce

The nematobacterial complex Heterorhabditis Photorhabdus as infection model for Drosophila immunity

Popis výsledku anglicky

Entomopathogenic nematodes (EPNs) of the genera Heterorhabditis and Steinernema are obligate and lethal insect parasites, in recent years they have been used increasingly as biological control agents for pest insects. Animals from the third developmentalstage of nematodes are called dauer juvenile (DJ) or infective juveniles (IJ). IJs occur free living in the soil and are capable of seeking out hosts and penetrate them through either the cuticle or natural orifices. EPNs are symbiotically associated with bacteria of either of the genera Photorhabdus and Xenorhabdus. The bacterial symbionts are essential to kill the insect host (usually within 24-48 hours) and to digest host tissues. Drosophila larvae are more resistant to nematode infection than Galleria mellonella where all larvae can be killed with low nematode dose. The tripartite model (Drosophila, nematodes, bacteria) was recently established by Hallem el al. (2007); we used their modified method to optimize conditions for infect

Druh

O - Ostatní výsledky

CEP obor

EC - Imunologie

OECD FORD obor

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Projekt

<a href="/cs/project/GP206%2F09%2FP470" target="_blank" >GP206/09/P470: Vliv inhibitorů biosyntézy eikosanoidů na imunitu zavíječe voskového Galleria mellonella</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2009

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů