Cell motility in early emerging apicomplexans with emphasis on gregarines and protococcidia

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F13%3A00066892" target="_blank" >RIV/00216224:14310/13:00066892 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Cell motility in early emerging apicomplexans with emphasis on gregarines and protococcidia

Popis výsledku v původním jazyce

Apicomplexa represent one of the most successful and diverse group of unicellular parasites exhibiting unique adaptations to their life style. Their motile invasive zoites use a unique conserved form of actin-based gliding motility. Since cytoskeletal elements play an important role in various life processes of Apicomplexa, they represent a potential target for chemotherapeutic intervention. Our intent is to investigate whether the glideosome concept, proposed in Toxoplasma, could be applied also to basal apicomplexan lineages. We focus on deep-branching groups, especially gregarines and protococcidians, restricted to invertebrates. These parasites exhibit diverse modes of locomotion depending on their cell architecture and surrounding environment, e.g.

Název v anglickém jazyce

Cell motility in early emerging apicomplexans with emphasis on gregarines and protococcidia

Popis výsledku anglicky

Apicomplexa represent one of the most successful and diverse group of unicellular parasites exhibiting unique adaptations to their life style. Their motile invasive zoites use a unique conserved form of actin-based gliding motility. Since cytoskeletal elements play an important role in various life processes of Apicomplexa, they represent a potential target for chemotherapeutic intervention. Our intent is to investigate whether the glideosome concept, proposed in Toxoplasma, could be applied also to basal apicomplexan lineages. We focus on deep-branching groups, especially gregarines and protococcidians, restricted to invertebrates. These parasites exhibit diverse modes of locomotion depending on their cell architecture and surrounding environment, e.g.

Druh

O - Ostatní výsledky

CEP obor

EG - Zoologie

OECD FORD obor

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Projekt

<a href="/cs/project/GBP505%2F12%2FG112" target="_blank" >GBP505/12/G112: ECIP - Evropské centrum ichtyoparazitologie</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů