Oral Fat Sensing and CD36 Gene Polymorphism in Algerian Lean and Obese Teenagers

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F15%3A00085113" target="_blank" >RIV/00216224:14310/15:00085113 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/67985904:_____/15:00453677

Výsledek na webu

<a href="http://dx.doi.org/10.3390/nu7115455" target="_blank" >http://dx.doi.org/10.3390/nu7115455</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/nu7115455" target="_blank" >10.3390/nu7115455</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Oral Fat Sensing and CD36 Gene Polymorphism in Algerian Lean and Obese Teenagers

Popis výsledku v původním jazyce

Growing number of evidences have suggested that oral fat sensing, mediated by a glycoprotein CD36 (cluster of differentiation 36), plays a significant role in the development of obesity. Indeed, a decreased expression of CD36 in some obese subjects is associated with high dietary fat intake. In the present study, we examined whether an increase in body mass index (BMI) is associated with altered oleic acid lingual detection thresholds and blood lipid profile in young Algerian teenagers (n = 165). The obese teenagers (n = 83; 14.01 ? 0.19 years; BMI z-score 2.67 ? 0.29) exhibited higher lingual detection threshold for oleic acid than lean participants (n = 82, 13.92 ? 0.23 years; BMI z-score 0.03 ? 0.0001). We also studied the association between rs1761667 polymorphism of CD36 gene and obesity. The AA and AG genotypes were more frequent in obese teenagers, whereas GG genotype was more common in lean participants. The A-allele frequency was higher in obese teenagers than that in lean chi

Název v anglickém jazyce

Oral Fat Sensing and CD36 Gene Polymorphism in Algerian Lean and Obese Teenagers

Popis výsledku anglicky

Growing number of evidences have suggested that oral fat sensing, mediated by a glycoprotein CD36 (cluster of differentiation 36), plays a significant role in the development of obesity. Indeed, a decreased expression of CD36 in some obese subjects is associated with high dietary fat intake. In the present study, we examined whether an increase in body mass index (BMI) is associated with altered oleic acid lingual detection thresholds and blood lipid profile in young Algerian teenagers (n = 165). The obese teenagers (n = 83; 14.01 ? 0.19 years; BMI z-score 2.67 ? 0.29) exhibited higher lingual detection threshold for oleic acid than lean participants (n = 82, 13.92 ? 0.23 years; BMI z-score 0.03 ? 0.0001). We also studied the association between rs1761667 polymorphism of CD36 gene and obesity. The AA and AG genotypes were more frequent in obese teenagers, whereas GG genotype was more common in lean participants. The A-allele frequency was higher in obese teenagers than that in lean chi

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

ED - Fyziologie

OECD FORD obor

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Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Nutrients

ISSN

2072-6643

e-ISSN

—

Svazek periodika

7

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

9

Strana od-do

9096-9104

Kód UT WoS článku

000365656900016

EID výsledku v databázi Scopus

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