Lone pair–pi interactions in biological systems: occurrence, function, and physical origin

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F17%3A00095188" target="_blank" >RIV/00216224:14310/17:00095188 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s00249-017-1210-1" target="_blank" >http://dx.doi.org/10.1007/s00249-017-1210-1</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00249-017-1210-1" target="_blank" >10.1007/s00249-017-1210-1</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Lone pair–pi interactions in biological systems: occurrence, function, and physical origin

Popis výsledku v původním jazyce

Review article that attempts to highlight some recent discoveries evidencing the important role which lone-pair–pi interactions, and anion–pi interactions in particular, play in stabilizing structure and affecting function of biomolecules. Special attention is paid to studies exploring the physical origin of these at first glance counterintuitive interactions between a lone-pair of electrons of one residue and the pi-cloud of another residue. Recent theoretical work went beyond the popular electrostatic model and inquired to which extent orbital interactions have to be taken into account. At least in one biologically relevant case- in that of anion-flavin interactions- a substantial charge-transfer component has been shown to operate.

Název v anglickém jazyce

Lone pair–pi interactions in biological systems: occurrence, function, and physical origin

Popis výsledku anglicky

Review article that attempts to highlight some recent discoveries evidencing the important role which lone-pair–pi interactions, and anion–pi interactions in particular, play in stabilizing structure and affecting function of biomolecules. Special attention is paid to studies exploring the physical origin of these at first glance counterintuitive interactions between a lone-pair of electrons of one residue and the pi-cloud of another residue. Recent theoretical work went beyond the popular electrostatic model and inquired to which extent orbital interactions have to be taken into account. At least in one biologically relevant case- in that of anion-flavin interactions- a substantial charge-transfer component has been shown to operate.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10610 - Biophysics

Projekt

<a href="/cs/project/GA14-14654S" target="_blank" >GA14-14654S: Studium fyzikální podstaty interakcí lone-pair-pi v biomolekulárních systémech. Role interakcí lone-pair-pi při stabilizaci proteinu Engrailed</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European Biophysics Journal With Biophysics Letters

ISSN

0175-7571

e-ISSN

—

Svazek periodika

46

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

729-737

Kód UT WoS článku

000415817400005

EID výsledku v databázi Scopus

2-s2.0-85018380842