Optimization of media cultivation for intestinal sulfate-reducing bacteria

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F17%3A00097798" target="_blank" >RIV/00216224:14310/17:00097798 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Optimization of media cultivation for intestinal sulfate-reducing bacteria

Popis výsledku v původním jazyce

Intestinal sulfate-reducing bacteria (SRB) are anaerobic microorganisms which make part of animal and human large intestine microbiota. Hydrogen sulfide is a final product of SRB metabolism. Its production in the high concentration has negative impact on epithelial cells of the large bowel. This toxic compound can be involved in intestinal inflammation and affects gastrointestinal motility, secretion and nociception, and leads to diseases like an ulcerative colitis, Crohn's disease or even cancer. Isolation of SRB from the mixture of human and animals’ microbiota and their cultivation is also difficult. Some species of SRB such as Bilophila wadsworthia and Lawsoni intracellularis are uncultured. Other genera of the Desulfovibrionaceae family also grow poorly in cultivation medium or are uncultured.

Název v anglickém jazyce

Optimization of media cultivation for intestinal sulfate-reducing bacteria

Popis výsledku anglicky

Intestinal sulfate-reducing bacteria (SRB) are anaerobic microorganisms which make part of animal and human large intestine microbiota. Hydrogen sulfide is a final product of SRB metabolism. Its production in the high concentration has negative impact on epithelial cells of the large bowel. This toxic compound can be involved in intestinal inflammation and affects gastrointestinal motility, secretion and nociception, and leads to diseases like an ulcerative colitis, Crohn's disease or even cancer. Isolation of SRB from the mixture of human and animals’ microbiota and their cultivation is also difficult. Some species of SRB such as Bilophila wadsworthia and Lawsoni intracellularis are uncultured. Other genera of the Desulfovibrionaceae family also grow poorly in cultivation medium or are uncultured.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10600 - Biological sciences

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů