Metabolic activity of sulfate-reducing bacteria from rodents with colitis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F18%3A00103553" target="_blank" >RIV/00216224:14310/18:00103553 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.degruyter.com/view/j/med.2018.13.issue-1/med-2018-0052/med-2018-0052.xml?format=INT" target="_blank" >https://www.degruyter.com/view/j/med.2018.13.issue-1/med-2018-0052/med-2018-0052.xml?format=INT</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1515/med-2018-0052" target="_blank" >10.1515/med-2018-0052</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Metabolic activity of sulfate-reducing bacteria from rodents with colitis

Popis výsledku v původním jazyce

Sulfate-reducing bacteria (SRB) are anaerobic microorganisms, which use sulfate as an electron acceptor in the process of dissimilatory sulfate reduction. The final metabolic product of these anaerobic microorganisms is hydrogen sulfide, which is known as toxic and can lead to damage to epithelial cells of the large intestine at high concentrations. Different genera of SRB are detected in the large intestine of healthy human and animals, and with diseases like Crohn’s disease and ulcerative colitis. SRB isolated from rodents with ulcerative colitis have produced 1.14 (mice) and 1.03 (rats) times more sulfide ions than healthy rodents. The species of Desulfovibrio genus are the most widespread among all SRB in the intestine. The object of our research was to observe and compare the difference of production of sulfide and reduction of sulfate in intestinal SRB isolated from healthy rodents and rodents with ulcerative colitis.

Název v anglickém jazyce

Metabolic activity of sulfate-reducing bacteria from rodents with colitis

Popis výsledku anglicky

Sulfate-reducing bacteria (SRB) are anaerobic microorganisms, which use sulfate as an electron acceptor in the process of dissimilatory sulfate reduction. The final metabolic product of these anaerobic microorganisms is hydrogen sulfide, which is known as toxic and can lead to damage to epithelial cells of the large intestine at high concentrations. Different genera of SRB are detected in the large intestine of healthy human and animals, and with diseases like Crohn’s disease and ulcerative colitis. SRB isolated from rodents with ulcerative colitis have produced 1.14 (mice) and 1.03 (rats) times more sulfide ions than healthy rodents. The species of Desulfovibrio genus are the most widespread among all SRB in the intestine. The object of our research was to observe and compare the difference of production of sulfide and reduction of sulfate in intestinal SRB isolated from healthy rodents and rodents with ulcerative colitis.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10606 - Microbiology

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Open Medicine

ISSN

2391-5463

e-ISSN

2391-5463

Svazek periodika

13

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

6

Strana od-do

344-349

Kód UT WoS článku

000444318200003

EID výsledku v databázi Scopus

2-s2.0-85054133625