Isoflavones

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F23%3A00130404" target="_blank" >RIV/00216224:14310/23:00130404 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/referenceworkentry/10.1007/978-3-030-81404-5_8-1" target="_blank" >https://link.springer.com/referenceworkentry/10.1007/978-3-030-81404-5_8-1</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-3-030-81404-5_8-1" target="_blank" >10.1007/978-3-030-81404-5_8-1</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Isoflavones

Popis výsledku v původním jazyce

Isoflavones, phenolic compounds with a 3-phenylchromen-4-one backbone, are plant-derived metabolites found primarily in the Fabaceae family. Hundreds of isoflavone structures have been identified so far. Regarding human nutrition, the most important of these are soybean isoflavones including daidzein, genistein, and glycitein. After ingestion, isoflavones are deglycosylated, demethylated, oxidized (or reduced), glucuronidated, or sulfated by enterocytes, liver cells, and intestinal microorganisms. Among the metabolites, daidzein metabolite equol has the greatest impact on human health. Due to their similarity to estrogens, equol and genistein, and to a lesser extent other isoflavones, exert estrogenic or antiestrogenic effects in mammals, leading to antimenopausal, cardioprotective, antiosteoporotic, and in the case of estrogen-related cancers, anticarcinogenic effects. Apart from these hormone-related activities, isoflavones possess antioxidant properties and influence several other biological processes. However, the health effects of food-derived isoflavones are dependent on the food matrices and also on the ability of intestinal microflora to produce equol. For the individuals who cannot produce equol, the consumption of milk is an alternative, as significant amounts of this metabolite are excreted into milk in cows fed feedstuffs rich in isoflavones. Thus, targeted cattle nutrition could result in the production of milk that can be considered a functional food.

Název v anglickém jazyce

Isoflavones

Popis výsledku anglicky

Isoflavones, phenolic compounds with a 3-phenylchromen-4-one backbone, are plant-derived metabolites found primarily in the Fabaceae family. Hundreds of isoflavone structures have been identified so far. Regarding human nutrition, the most important of these are soybean isoflavones including daidzein, genistein, and glycitein. After ingestion, isoflavones are deglycosylated, demethylated, oxidized (or reduced), glucuronidated, or sulfated by enterocytes, liver cells, and intestinal microorganisms. Among the metabolites, daidzein metabolite equol has the greatest impact on human health. Due to their similarity to estrogens, equol and genistein, and to a lesser extent other isoflavones, exert estrogenic or antiestrogenic effects in mammals, leading to antimenopausal, cardioprotective, antiosteoporotic, and in the case of estrogen-related cancers, anticarcinogenic effects. Apart from these hormone-related activities, isoflavones possess antioxidant properties and influence several other biological processes. However, the health effects of food-derived isoflavones are dependent on the food matrices and also on the ability of intestinal microflora to produce equol. For the individuals who cannot produce equol, the consumption of milk is an alternative, as significant amounts of this metabolite are excreted into milk in cows fed feedstuffs rich in isoflavones. Thus, targeted cattle nutrition could result in the production of milk that can be considered a functional food.

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

10608 - Biochemistry and molecular biology

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Handbook of Food Bioactive Ingredients : Properties and Applications

ISBN

9783030814045

Počet stran výsledku

27

Strana od-do

1-27

Počet stran knihy

990

Název nakladatele

Springer

Místo vydání

Cham

Kód UT WoS kapitoly

—