Calibration of Chiral Compounds with Self-Internal Standard. Application to Determination of S(-)-propranolol Hydrochloride by Capillary Zone Electrophoresis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14330%2F02%3A00007232" target="_blank" >RIV/00216224:14330/02:00007232 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Calibration of Chiral Compounds with Self-Internal Standard. Application to Determination of S(-)-propranolol Hydrochloride by Capillary Zone Electrophoresis

Popis výsledku v původním jazyce

A new method of calibration designed for chiral compounds named: Calibration with Self-internal Standard, is suggested. Here, the second enantiomer serves as the internal standard, the total concentration of both enantiomers is known and kept constant. The method is an alternative to the commonly used calibration with an internal standard being a chemically different compound. The applicability of the method is demonstrated on the calibration of propranolol hydrochloride in capillary zone electrophoresis. Statistical characteristics of the method are compared to calibration without an internal standard and with L-tryptophan as internal standard.

Název v anglickém jazyce

Calibration of Chiral Compounds with Self-Internal Standard. Application to Determination of S(-)-propranolol Hydrochloride by Capillary Zone Electrophoresis

Popis výsledku anglicky

A new method of calibration designed for chiral compounds named: Calibration with Self-internal Standard, is suggested. Here, the second enantiomer serves as the internal standard, the total concentration of both enantiomers is known and kept constant. The method is an alternative to the commonly used calibration with an internal standard being a chemically different compound. The applicability of the method is demonstrated on the calibration of propranolol hydrochloride in capillary zone electrophoresis. Statistical characteristics of the method are compared to calibration without an internal standard and with L-tryptophan as internal standard.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2002

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Chromatographia

ISSN

0009-5893

e-ISSN

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Svazek periodika

56

Číslo periodika v rámci svazku

9/10

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

7

Strana od-do

597

Kód UT WoS článku

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EID výsledku v databázi Scopus

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