On Proper Simulation of Chromatin Structure in Static Images As Well As in Time-Lapse Sequences in Fluorescence Microscopy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14330%2F15%3A00080650" target="_blank" >RIV/00216224:14330/15:00080650 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1109/ISBI.2015.7163972" target="_blank" >http://dx.doi.org/10.1109/ISBI.2015.7163972</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1109/ISBI.2015.7163972" target="_blank" >10.1109/ISBI.2015.7163972</a>

Jazyk výsledku

angličtina

Název v původním jazyce

On Proper Simulation of Chromatin Structure in Static Images As Well As in Time-Lapse Sequences in Fluorescence Microscopy

Popis výsledku v původním jazyce

In fluorescence microscopy, where the benchmark datasets for validating the various image analysis methods are difficult to obtain, a great demand is either for manually annotated real image data or for computer generated ones. In the last two decades, the latter case has become more and more accessible due to an increasing computer capabilities. However, the development of elaborate models, especially in the field of fluorescence microscopy imaging, is less progressive. In this paper, we propose a novel approach, based on well established concepts, to properly imitate the structure of chromatin inside the cell nucleus as well as its dynamics. The performance of the approach was quantitatively evaluated against the real data. The results show that theproduced images are sufficiently plausible and visually resemble their real counter parts, both for fixed and living cells.

Název v anglickém jazyce

On Proper Simulation of Chromatin Structure in Static Images As Well As in Time-Lapse Sequences in Fluorescence Microscopy

Popis výsledku anglicky

In fluorescence microscopy, where the benchmark datasets for validating the various image analysis methods are difficult to obtain, a great demand is either for manually annotated real image data or for computer generated ones. In the last two decades, the latter case has become more and more accessible due to an increasing computer capabilities. However, the development of elaborate models, especially in the field of fluorescence microscopy imaging, is less progressive. In this paper, we propose a novel approach, based on well established concepts, to properly imitate the structure of chromatin inside the cell nucleus as well as its dynamics. The performance of the approach was quantitatively evaluated against the real data. The results show that theproduced images are sufficiently plausible and visually resemble their real counter parts, both for fixed and living cells.

Druh

D - Stať ve sborníku

CEP obor

IN - Informatika

OECD FORD obor

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Projekt

<a href="/cs/project/GA14-22461S" target="_blank" >GA14-22461S: Vývoj a studium metod pro kvantifikaci živých buněk</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Proceedings of 2015 IEEE International Symposium on Biomedical Imaging

ISBN

9781479923748

ISSN

1945-7928

e-ISSN

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Počet stran výsledku

5

Strana od-do

712-716

Název nakladatele

Engineering in Medicine and Biology Society

Místo vydání

Stoughton (WI, USA)

Místo konání akce

New York

Datum konání akce

1. 1. 2015

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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