Rapid Determination of Lead in Submicroliter Samples of Whole Blood using Diode Laser Thermal Vaporization

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F12%3A00057420" target="_blank" >RIV/00216224:14740/12:00057420 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Rapid Determination of Lead in Submicroliter Samples of Whole Blood using Diode Laser Thermal Vaporization

Popis výsledku v původním jazyce

A method for determination of trace elements in submicroliter sample volumes, diode laser thermal vaporization (DLTV) inductively-coupled plasma mass spectrometry (ICP-MS) is presented. Analyte is desorbed from a substrate, such as paper or cellulose containing a suitable absorber, using a continuous-wave diode laser. The laser induces pyrolysis of the substrate and the generated aerosol is carried out into the plasma torch. Unlike laser ablation, DLTV does not require an expensive high-energy pulse laser, which makes it a promising alternative to nebulizers. Analysis of lead in whole blood is demonstrated. Advantages of the method, simplicity, speed, easy archiving and transportation of samples and low cost, are presented. Selection of experimental arrangement and laser wavelength as well as optimization of experimental conditions, e.g., raster type, scan speed, additives etc. was examined.

Název v anglickém jazyce

Rapid Determination of Lead in Submicroliter Samples of Whole Blood using Diode Laser Thermal Vaporization

Popis výsledku anglicky

A method for determination of trace elements in submicroliter sample volumes, diode laser thermal vaporization (DLTV) inductively-coupled plasma mass spectrometry (ICP-MS) is presented. Analyte is desorbed from a substrate, such as paper or cellulose containing a suitable absorber, using a continuous-wave diode laser. The laser induces pyrolysis of the substrate and the generated aerosol is carried out into the plasma torch. Unlike laser ablation, DLTV does not require an expensive high-energy pulse laser, which makes it a promising alternative to nebulizers. Analysis of lead in whole blood is demonstrated. Advantages of the method, simplicity, speed, easy archiving and transportation of samples and low cost, are presented. Selection of experimental arrangement and laser wavelength as well as optimization of experimental conditions, e.g., raster type, scan speed, additives etc. was examined.

Druh

O - Ostatní výsledky

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů