Identification of the Sequence and the Length of Telomere DNA

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F23%3A00134743" target="_blank" >RIV/00216224:14740/23:00134743 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/protocol/10.1007/978-1-0716-3226-0_18" target="_blank" >https://link.springer.com/protocol/10.1007/978-1-0716-3226-0_18</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-1-0716-3226-0_18" target="_blank" >10.1007/978-1-0716-3226-0_18</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Identification of the Sequence and the Length of Telomere DNA

Popis výsledku v původním jazyce

Telomeres are essential nucleoprotein structures at the very ends of linear eukaryote chromosomes. They shelter the terminal genome territories against degradation and prevent the natural chromosome ends from being recognized by repair mechanisms as double-strand DNA breaks. There are two basic characteristics of telomeric DNA, its sequence and its length. The telomere sequence is important as a “landing area” for specific telomere-binding proteins, which function as signals and moderate the interactions required for correct telomere function. While the sequence forms the proper “landing surface” of telomeric DNA, its length is similarly important. Too short or exceptionally long telomere DNA cannot perform its function properly. In this chapter, methods for the investigation of these two basic telomere DNA characteristics are described, namely, telomere motif identification and telomere length measurement.

Název v anglickém jazyce

Identification of the Sequence and the Length of Telomere DNA

Popis výsledku anglicky

Telomeres are essential nucleoprotein structures at the very ends of linear eukaryote chromosomes. They shelter the terminal genome territories against degradation and prevent the natural chromosome ends from being recognized by repair mechanisms as double-strand DNA breaks. There are two basic characteristics of telomeric DNA, its sequence and its length. The telomere sequence is important as a “landing area” for specific telomere-binding proteins, which function as signals and moderate the interactions required for correct telomere function. While the sequence forms the proper “landing surface” of telomeric DNA, its length is similarly important. Too short or exceptionally long telomere DNA cannot perform its function properly. In this chapter, methods for the investigation of these two basic telomere DNA characteristics are described, namely, telomere motif identification and telomere length measurement.

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

10611 - Plant sciences, botany

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Plant Cytogenetics and Cytogenomics : Plant Cytogenetics and Cytogenomics

ISBN

9781071632253

Počet stran výsledku

18

Strana od-do

285-302

Počet stran knihy

568

Název nakladatele

Springer Nature

Místo vydání

New York

Kód UT WoS kapitoly

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