A perspective on COVID-19 hospitalised patients across Europe: data from the ENDCOVID CRC

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A90034%2F24%3A00138354" target="_blank" >RIV/00216224:90034/24:00138354 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.ersnet.org/wp-content/uploads/2024/09/Congress-Programme-2024-0409.pdf" target="_blank" >https://www.ersnet.org/wp-content/uploads/2024/09/Congress-Programme-2024-0409.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1183/13993003.congress-2024.PA1511" target="_blank" >10.1183/13993003.congress-2024.PA1511</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A perspective on COVID-19 hospitalised patients across Europe: data from the ENDCOVID CRC

Popis výsledku v původním jazyce

The COVID-19 pandemic has represented a relevant burden on European healthcare systems in the past few years. Differences in the hospitalised population features, treatment regimens and outcomes across European Countries are expected. An international, multicentric, observational, cross-sectional study has been conducted by the END-COVID clinical research collaboration through the creation of a federation of registries enrolling hospitalised COVID-19 patients at local or national level. Data sharing was achieved only through median [IQR] and absolute numbers (%) of relevant variables, with no individual participant data dissemination. 11 registries from 8 different countries enrolling a total of 19,461 patients have been included in the analysis. All patients had a confirmed SARS-CoV-2 infection. The median age ranged between 56 (Romania) and 80 years (Italy), while male patients ranged from 51.2% (Ireland) to 65.7% (Netherlands). The proportion of patients achieving the diagnosis with a PCR nasal swab test ranged between 69.8% (Czech Republic) and 100.0% (Italy, Netherlands, and Ireland). Southern European centres used both systemic antibiotics (56.0% vs 68.3% vs 74.3%, P &lt; 0.0001) and systemic corticosteroids (40.4% vs 61.1% vs 64.4%, P &lt; 0.0001) less frequently than Northern and Eastern European ones. Access to Intensive Care Unit was less common in Southern European centres compared to Northern and Eastern European centres (10.1% vs 21.5% vs 22.7%, P &lt; 0.0001). In-hospital mortality ranged between 5.7% (Spain) and 33.9% (Croatia). We highlighted substantial differences in the population features, treatment regimens and outcomes of COVID-19 hospitalised patients across Europe.

Název v anglickém jazyce

A perspective on COVID-19 hospitalised patients across Europe: data from the ENDCOVID CRC

Popis výsledku anglicky

The COVID-19 pandemic has represented a relevant burden on European healthcare systems in the past few years. Differences in the hospitalised population features, treatment regimens and outcomes across European Countries are expected. An international, multicentric, observational, cross-sectional study has been conducted by the END-COVID clinical research collaboration through the creation of a federation of registries enrolling hospitalised COVID-19 patients at local or national level. Data sharing was achieved only through median [IQR] and absolute numbers (%) of relevant variables, with no individual participant data dissemination. 11 registries from 8 different countries enrolling a total of 19,461 patients have been included in the analysis. All patients had a confirmed SARS-CoV-2 infection. The median age ranged between 56 (Romania) and 80 years (Italy), while male patients ranged from 51.2% (Ireland) to 65.7% (Netherlands). The proportion of patients achieving the diagnosis with a PCR nasal swab test ranged between 69.8% (Czech Republic) and 100.0% (Italy, Netherlands, and Ireland). Southern European centres used both systemic antibiotics (56.0% vs 68.3% vs 74.3%, P &lt; 0.0001) and systemic corticosteroids (40.4% vs 61.1% vs 64.4%, P &lt; 0.0001) less frequently than Northern and Eastern European ones. Access to Intensive Care Unit was less common in Southern European centres compared to Northern and Eastern European centres (10.1% vs 21.5% vs 22.7%, P &lt; 0.0001). In-hospital mortality ranged between 5.7% (Spain) and 33.9% (Croatia). We highlighted substantial differences in the population features, treatment regimens and outcomes of COVID-19 hospitalised patients across Europe.

Druh

O - Ostatní výsledky

CEP obor

—

OECD FORD obor

30230 - Other clinical medicine subjects

Projekt

—

Návaznosti

—

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů