Combined Macro-/Mesoporous Microelectrode Arrays for Low-Noise Extracellular Recording of Neural Networks

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F12%3A39895329" target="_blank" >RIV/00216275:25310/12:39895329 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1152/jn.00711.2011" target="_blank" >http://dx.doi.org/10.1152/jn.00711.2011</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1152/jn.00711.2011" target="_blank" >10.1152/jn.00711.2011</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Combined Macro-/Mesoporous Microelectrode Arrays for Low-Noise Extracellular Recording of Neural Networks

Popis výsledku v původním jazyce

Microelectrode arrays (MEAs) are appealing tools to probe large neural ensembles and build neural prostheses. Microelectronics microfabrication technologies now allow building high-density MEAs containing several hundreds of microelectrodes. However, several major problems become limiting factors when the size of the microelectrodes decreases. In particular, regarding recording of neural activity, the intrinsic noise level of a microelectrode dramatically increases when the size becomes small (typicallybelow 20-mu m diameter). Here, we propose to overcome this limitation using a template-based, single-scale meso-or two-scale macro-/mesoporous modification of the microelectrodes, combining the advantages of an overall small geometric surface and an active surface increased by several orders of magnitude. For this purpose, standard platinum MEAs were covered with a highly porous platinum overlayer obtained by lyotropic liquid crystal templating possibly in combination with a microsphere

Název v anglickém jazyce

Combined Macro-/Mesoporous Microelectrode Arrays for Low-Noise Extracellular Recording of Neural Networks

Popis výsledku anglicky

Microelectrode arrays (MEAs) are appealing tools to probe large neural ensembles and build neural prostheses. Microelectronics microfabrication technologies now allow building high-density MEAs containing several hundreds of microelectrodes. However, several major problems become limiting factors when the size of the microelectrodes decreases. In particular, regarding recording of neural activity, the intrinsic noise level of a microelectrode dramatically increases when the size becomes small (typicallybelow 20-mu m diameter). Here, we propose to overcome this limitation using a template-based, single-scale meso-or two-scale macro-/mesoporous modification of the microelectrodes, combining the advantages of an overall small geometric surface and an active surface increased by several orders of magnitude. For this purpose, standard platinum MEAs were covered with a highly porous platinum overlayer obtained by lyotropic liquid crystal templating possibly in combination with a microsphere

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CG - Elektrochemie

OECD FORD obor

—

Projekt

<a href="/cs/project/LC06035" target="_blank" >LC06035: Centrum biofyzikální chemie, bioelektrochemie a bioanalýzy. Nové nástroje pro genomiku, proteomiku a biomedicínu.</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

JOURNAL OF NEUROPHYSIOLOGY

ISSN

0022-3077

e-ISSN

—

Svazek periodika

108

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

11

Strana od-do

1793-1803

Kód UT WoS článku

000309000100021

EID výsledku v databázi Scopus

—